Immunogenicity 4130

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
SEC16A
Transcript ID
uc004chr.3
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (385 aa)
MDLLP
1
TSILL
6
ASLWI
11
CSHLH
16
PPGVS
21
VDLPP
26
TSILL
31
VSLWI
36
CSHLH
41
PPGVS
46
VDRPP
51
PPSSW
56
CLCGS
61
PPTSI
66
LLVSL
71
WICSP
76
PPSSW
81
CLCGS
86
APTSI
91
LLVSL
96
WIWRL
101
WGLTE
106
GESWF
111
FRWLP
116
GKKKT
121
EAYLP
126
DDKNK
131
SIVWD
136
EKKNQ
141
WVNLN
146
EPEEE
151
KKAPP
156
PPPTS
161
MPKTV
166
QAAPP
171
ALPGP
176
PGAPV
181
NMYSR
186
RAAGT
191
RARYV
196
DVLNP
201
SGTQR
206
SEPAL
211
APADF
216
VAPLA
221
PLPIP
226
SNLFV
231
PTPVS
236
SVRPQ
241
GRSGR
246
NDGLL
251
ALSSP
256
DAEEP
261
QLPDG
266
TGREG
271
PAAAR
276
GLANP
281
EPAPE
286
PKVLS
291
SAASL
296
PGSEL
301
PSSRP
306
EGSQG
311
GELSR
316
CSSMS
321
SLSRE
326
VSQHF
331
NQAPG
336
DLPAA
341
GGPPS
346
GAMPF
351
YNPAQ
356
LAQAC
361
ATSGS
366
SRLGR
371
IGQRK
376
HLVLN
381
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 23
Mut AA position:
11 (11 in Wild Type peptide)
Alignment
Wild Type:
"MDLLPTSILLASLWICSHLHPPG
||||||||||.||||||||||||
Mutant:
MDLLPTSILLVSLWICSHLHPPG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SEC16A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay