Immunogenicity 4143

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SCML2
Transcript ID
uc011miz.1
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (543 aa)
MKLEA
1
RDPRN
6
ATSVC
11
IATVI
16
GITGA
21
RLRLR
26
LDGSD
31
NRNDF
36
WRLVD
41
SPDIQ
46
PVGTC
51
EKEGD
56
LLQPP
61
LGYQM
66
NTSSW
71
PMFLL
76
KTLNG
81
SEMAS
86
ATLFK
91
KEPPK
96
PPLNN
101
FKVGM
106
KLEAI
111
DKKNP
116
YLICP
121
ATIGD
126
VKGDE
131
VHITF
136
DGWSG
141
AFDYW
146
CKYDS
151
RDIFP
156
AGWCR
161
LTGDV
166
LQPPG
171
TSVPI
176
VKNIA
181
KTESS
186
PSEAS
191
QHSMQ
196
SPQKT
201
TLILP
206
TQQVR
211
RSSRI
216
KPPGP
221
TAVPK
226
RSSSV
231
KNITP
236
RKKGP
241
NSGKK
246
EKPLP
251
VICST
256
SAASL
261
KSLTR
266
DRGML
271
YKDVA
276
SGPCK
281
IVMST
286
VCVYV
291
NKHGN
296
FGPHL
301
DPKRI
306
QQLPD
311
HFGPG
316
PVNVV
321
LRRIV
326
QACVD
331
CALET
336
KTVFG
341
YLKPD
346
NRGGE
351
VITAS
356
FDGET
361
HSIQL
366
PPVNS
371
ASFAL
376
RFLEN
381
FCHSL
386
QCDNL
391
LSSQP
396
FSSSR
401
GHTHS
406
SAEHD
411
KNQSA
416
KEDVT
421
ERQST
426
KRSPQ
431
QTVPY
436
VVPLS
441
PKLPK
446
TKEYA
451
SEGEP
456
LFAGG
461
SAIPK
466
EENLS
471
EDSKS
476
SSLNS
481
GNYLN
486
PACRN
491
PMYIH
496
TSVSQ
501
DFSRS
506
VPGTT
511
SSPLV
516
GDISP
521
KSSPH
526
EVKFQ
531
MQRKS
536
EGN
541
Mutation Information
DNA mutation:
None
Peptide Range:
340 ~ 364
Mut AA position:
352 (13 in Wild Type peptide)
Alignment
Wild Type:
"TKTVFGYLKPDNRGGEVITASFDGE
||||||||||||.||||||||||||
Mutant:
TKTVFGYLKPDNHGGEVITASFDGE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SCML2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay