Immunogenicity 4150

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
RPGR
Transcript ID
uc004ded.1
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (1152 aa)
MREPE
1
ELMPD
6
SGAVF
11
TFGKS
16
KFAEN
21
NPGKF
26
WFKND
31
VPVHL
36
SCGDE
41
HSAVV
46
TGNNK
51
LYMFG
56
SNNWG
61
QLGLG
66
SKSAI
71
SKPTC
76
VKALK
81
PEKVK
86
LAACG
91
RNHTL
96
VSTEG
101
GNVYA
106
TGGNN
111
EGQLG
116
LGDTE
121
ERNTF
126
HVISF
131
FTSEH
136
KIKQL
141
SAGSN
146
TSAAL
151
TEDGR
156
LFMWG
161
DNSEG
166
QIGLK
171
NVSNV
176
CVPQQ
181
VTIGK
186
PVSWI
191
SCGYY
196
HSAFV
201
TTDGE
206
LYVFG
211
EPENG
216
KLGLP
221
NQLLG
226
NHRTP
231
QLVSE
236
IPEKV
241
IQVAC
246
GGEHT
251
VVLTE
256
NAVYT
261
FGLGQ
266
FGQLG
271
LGTFL
276
FETSE
281
PKVIE
286
NIRDQ
291
TISYI
296
SCGEN
301
HTALI
306
TDIGL
311
MYTFG
316
DGRHG
321
KLGLG
326
LENFT
331
NHFIP
336
TLCSN
341
FLRFI
346
VKLVA
351
CGGCH
356
MVVFA
361
APHRG
366
VAKEI
371
EFDEI
376
NDTCL
381
SVATF
386
LPYSS
391
LTSGN
396
VLQRT
401
LSARM
406
RRRER
411
ERSPD
416
SFSMR
421
RTLPP
426
IEGTL
431
GLSAC
436
FLPNS
441
VFPRC
446
SERNL
451
QESVL
456
SEQDL
461
MQPEE
466
PDYLL
471
DEMTK
476
EAEID
481
NSSTV
486
ESLGE
491
TTDIL
496
NMTHI
501
MSLNS
506
NEKSL
511
KLSPV
516
QKQKK
521
QQTIG
526
ELTQD
531
TALTE
536
NDDSD
541
EYEEM
546
SEMKE
551
GKACK
556
QHVSQ
561
GIFMT
566
QPATT
571
IEAFS
576
DEEVE
581
IPEEK
586
EGAED
591
SKGNG
596
IEEQE
601
VEANE
606
ENVKV
611
HGGRK
616
EKTEI
621
LSDDL
626
TDKAE
631
VSEGK
636
AKSVG
641
EAEDG
646
PEGRG
651
DGTCE
656
EGSSG
661
AEHWQ
666
DEERE
671
KGEKD
676
KGRGE
681
MERPG
686
EGEKE
691
LAEKE
696
EWKKR
701
DGEEQ
706
EQKER
711
EQGHQ
716
KERNQ
721
EMEEG
726
GEEEH
731
GEGEE
736
EEGDR
741
EEEEE
746
KEGEG
751
KEEGE
756
GEEVE
761
GEREK
766
EEGER
771
KKEER
776
AGKEE
781
KGEEE
786
GDQGE
791
GEEEE
796
TEGRG
801
EEKEE
806
GGEVE
811
GGEVE
816
EGKGE
821
REEEE
826
EEGEG
831
EEEEG
836
EGEEE
841
EGEGE
846
EEEGE
851
GKGEE
856
EGEEG
861
EGEEE
866
GEEGE
871
GEGEE
876
EEGEG
881
EGEEE
886
GEGEG
891
EEEEG
896
EGEGE
901
EEGEG
906
EGEEE
911
EGEGK
916
GEEEG
921
EEGEG
926
EGEEE
931
EGEGE
936
GEDGE
941
GEGEE
946
EEGEW
951
EGEEE
956
EGEGE
961
GEEEG
966
EGEGE
971
EGEGE
976
GEEEE
981
GEGEG
986
EEEEG
991
EEEGE
996
EEGEG
1001
EEEGE
1006
GEGEE
1011
EEEGE
1016
VEGEV
1021
EGEEG
1026
EGEGE
1031
EEEGE
1036
EEGEE
1041
REKEG
1046
EGEEN
1051
RRNRE
1056
EEEEE
1061
EGKYQ
1066
ETGEE
1071
ENERQ
1076
DGEEY
1081
KKVSK
1086
IKGSV
1091
KYGKH
1096
KTYQK
1101
KSVTN
1106
TQGNG
1111
KEQRS
1116
KMPVQ
1121
SKRLL
1126
KNGPS
1131
GSKKF
1136
WNNVL
1141
PHYLE
1146
LK
1151
Mutation Information
DNA mutation:
None
Peptide Range:
967 ~ 991
Mut AA position:
979 (13 in Wild Type peptide)
Alignment
Wild Type:
"EEEGEGEGEEGEGEGEEEEGEGEGE
||||||||||||.||||||||||||
Mutant:
EEEGEGEGEEGEWEGEEEEGEGEGE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RPGR

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay