Immunogenicity 4161
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DGKK
Transcript ID
uc010njr.2
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1271 aa)
MDRGA
1
AAAQG
6
TAPPQ
11
DGEQP
16
AESPE
21
PPPPW
26
PPPPP
31
PPAPP
36
PAPPL
41
LSEAS
46
PEPIP
51
EPCPE
56
LAPGP
61
CPEAT
66
SESAT
71
ELYTE
76
PTPEP
81
ATEPA
86
SEPAP
91
EPATE
96
PAPEP
101
ATEPA
106
PEPAP
111
EPATE
116
SAPEP
121
TPEPA
126
LESVP
131
EPAPE
136
LTPEV
141
APELA
146
PEPTP
151
EPVTE
156
LAPEF
161
CPEAA
166
PEFRP
171
SPAPC
176
LLQCP
181
VDTRE
186
RGLKT
191
SPSPS
196
PSPSP
201
RTPMS
206
WSRIK
211
KILKE
216
GPMLK
221
NCNSF
226
KRWKL
231
RYFLV
236
QGQKL
241
YFAHH
246
PAFAH
251
FETID
256
LSQAT
261
VAESS
266
CRNLC
271
HSFCV
276
ITPQR
281
KITLA
286
APNRK
291
DMEEW
296
INIIK
301
TIQQG
306
EIYKI
311
PAAEN
316
NPFLV
321
GMHCW
326
YSSYS
331
HRTQH
336
CNVCR
341
ESIPA
346
LSRDA
351
IICEV
356
CKVKS
361
HRLCA
366
LRASK
371
DCKWN
376
TLSIT
381
DDLLL
386
PADEV
391
NMPHQ
396
WVEGN
401
MPVSS
406
QCAVC
411
HESCG
416
SYQRL
421
QDFRC
426
LWCNS
431
TVHDD
436
CRRRF
441
SKECC
446
FRSHR
451
SSVIP
456
PTALS
461
DPKGD
466
GQLVV
471
SSDFW
476
NLDWS
481
SACSC
486
PLLIF
491
INSKS
496
GDHQG
501
IVFLR
506
KFKQY
511
LNPSQ
516
VFDLL
521
KGGPE
526
AGLSM
531
FKNFA
536
RFRIL
541
VCGGD
546
GSVSW
551
VLSLI
556
DAFGL
561
HEKCQ
566
LAVIP
571
LGTGN
576
DLARV
581
LGWGA
586
FWNKS
591
KSPLD
596
ILNRV
601
EQASV
606
RILDR
611
WSVMI
616
RETPR
621
QTPLL
626
KGQVE
631
MDVPR
636
FEAAA
641
IQHLE
646
SAATE
651
LNKIL
656
KAKYP
661
TEMII
666
ATRFL
671
CSAVE
676
DFVVD
681
IVKAW
686
GQIKQ
691
NNTAI
696
VSVIL
701
KSDLM
706
YDRLS
711
VLIDV
716
LAEEA
721
AATSA
726
EKSAT
731
EYADS
736
SKADR
741
KPFIP
746
QIDHI
751
AKCKL
756
ELATK
761
AQSLQ
766
KSLKL
771
IIFQV
776
EQALD
781
EESRQ
786
TISVK
791
NFSST
796
FFLED
801
DPEDI
806
NQTSP
811
RRRSR
816
RGTLS
821
SISSL
826
KSEDL
831
DNLNL
836
DHLHF
841
TPESI
846
RFKEK
851
CVMNN
856
YFGIG
861
LDAKI
866
SLDFN
871
TRRDE
876
HPGQY
881
NSRLK
886
NKMWY
891
GLLGT
896
KELLQ
901
RSYRK
906
LEERV
911
HLECD
916
GETIS
921
LPNLQ
926
GIVVL
931
NITSY
936
AGGIN
941
FWGSN
946
TATTE
951
YEAPA
956
IDDGK
961
LEVVA
966
IFGSV
971
QMAMS
976
RIINL
981
HHHRI
986
AQCHE
991
VMITI
996
DGEEG
1001
IPVQV
1006
DGEAW
1011
IQRPG
1016
LIKIR
1021
YKNAA
1026
QMLTR
1031
DRDFE
1036
NSMKM
1041
WEYKH
1046
TEIQA
1051
APQPQ
1056
LDFQD
1061
SQESL
1066
SDEEY
1071
AQMQH
1076
LARLA
1081
ENLIS
1086
KLNDL
1091
SKIHQ
1096
HVSVL
1101
MGSVN
1106
ASANI
1111
LNDIF
1116
YGQDS
1121
GNEMG
1126
AASCI
1131
PIETL
1136
SRNDA
1141
VDVTF
1146
SLKGL
1151
YDDTT
1156
AFLDE
1161
KLLRS
1166
AEDET
1171
ALQSA
1176
LDAMN
1181
KEFKK
1186
LSEID
1191
WMNPI
1196
FVPEE
1201
KSSDT
1206
DSRSL
1211
RLKIK
1216
FPKLG
1221
KKKVE
1226
EERKP
1231
KSGQS
1236
VQSFI
1241
GNLWH
1246
RRHRE
1251
DEAEG
1256
DDPLT
1261
PSRSQ
1266
L
1271
Mutation Information
DNA mutation:
None
Peptide Range:
490 ~ 514
Mut AA position:
502 (13 in Wild Type peptide)
Alignment
Wild Type:
"CPLLIFINSKSGDHQGIVFLRKFKQ
||||||||||||.||||||||||||
Mutant:
CPLLIFINSKSGNHQGIVFLRKFKQ"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) DGKK
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay