Immunogenicity 417
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SETBP1
Transcript ID
None
HLA INFO
A*66:01
TCR INFO
No TCR info found!
Full length protein sequence (1596 aa)
MESRE
1
TLSSS
6
RQRGG
11
ESDFL
16
PVSSA
21
KPPAA
26
PGCAG
31
EPLLS
36
TPGPG
41
KGIPV
46
GGERM
51
EPEEE
56
DELGS
61
GRDVD
66
SNSNA
71
DSEKW
76
VAGDG
81
LEEQE
86
FSIKE
91
ANFTE
96
GSLKL
101
KIQTT
106
KRAKK
111
PPKNL
116
ENYIC
121
PPEIK
126
ITIKQ
131
SGDQK
136
VSRAG
141
KNSKA
146
TKEEE
151
RSHSK
156
KKLLT
161
ASDLA
166
ASDLK
171
GFQPQ
176
AYERP
181
QKHST
186
LHYDT
191
GLPQD
196
FTGDT
201
LKPKH
206
QQKSS
211
SQNHM
216
DWSTN
221
SDSGP
226
VTQNC
231
FISPE
236
SGRET
241
ASTSK
246
IPALE
251
PVASF
256
AKAQG
261
KKGSA
266
GNTWS
271
QLSNN
276
NKDLL
281
LGGVA
286
PSPSS
291
HSSPA
296
PPSSS
301
AECNG
306
LQPLV
311
DQDGG
316
GTKEP
321
PEPPT
326
VGSKK
331
KSSKK
336
DVISQ
341
TIPNP
346
DLDWV
351
KNAQK
356
AFDNT
361
EGKRE
366
GYSAD
371
SAQEA
376
SPARQ
381
NVSSA
386
SNPEN
391
DSSHV
396
RITIP
401
IKAPS
406
LDPTN
411
HKRKK
416
RQSIK
421
AVVEK
426
IMPEK
431
ALASG
436
ITMSS
441
EVVNR
446
ILSNS
451
EGNKK
456
DPRVP
461
KLSKM
466
IENES
471
PSVGL
476
ETGGN
481
AEKVI
486
PGGVS
491
KPRKP
496
PMVMT
501
PPTCT
506
DHSPS
511
RKLPE
516
IQHPK
521
FAAKR
526
RWTCS
531
KPKPS
536
TMLRE
541
AVMAT
546
SDKLM
551
LEPPS
556
AYPIT
561
PSSPL
566
YTNTD
571
SLTVI
576
TPVKK
581
KRGRP
586
KKQPL
591
LTVET
596
IHEGT
601
STSPV
606
SPISR
611
EFPGT
616
KKRKR
621
RRNLA
626
KLAQL
631
VPGED
636
KPMSE
641
MKFHK
646
KVGKL
651
GVLDK
656
KTIKT
661
INKMK
666
TLKRK
671
NILNQ
676
ILSCS
681
SSVAL
686
KAKAP
691
PETSP
696
GAAAI
701
ESKLG
706
KQINV
711
SKRGT
716
IYIGK
721
KRGRK
726
PRAEL
731
PPPSE
736
EPKTA
741
IKHPR
746
PVSSQ
751
PDVPA
756
VPSNF
761
QSLVA
766
SSPAA
771
MHPLS
776
TQLGG
781
SNGNL
786
SPAST
791
ETNFS
796
ELKTM
801
PNLQP
806
ISALP
811
TKTQK
816
GIHSG
821
TWKLS
826
PPRLM
831
ANSPS
836
HLCEI
841
GSLKE
846
ITLSP
851
VSESH
856
SEETI
861
PSDSG
866
IGTDN
871
NSTSD
876
QAEKS
881
SESRR
886
RYSFD
891
FCSLD
896
NPEAI
901
PSDTS
906
TKNRH
911
GHRQK
916
HLIVD
921
NFLAH
926
ESLKK
931
PKHKR
936
KRKSL
941
QNRDD
946
LQFLA
951
DLEEL
956
ITKFQ
961
VFRIS
966
HRSYT
971
FYHEN
976
PYPSI
981
FRINF
986
DHYYP
991
VPYIQ
996
YDPLL
1001
YLRRT
1006
SDLKS
1011
KKKRG
1016
RPAKT
1021
NDTMT
1026
KVPFL
1031
QGFSY
1036
PIPSG
1041
SYYAP
1046
YGMPY
1051
TSMPM
1056
MNLGY
1061
YGQYP
1066
APLYL
1071
SHTLG
1076
AASPF
1081
MRPTV
1086
PPPQF
1091
HTNSH
1096
VKMSG
1101
AAKHK
1106
AKHGV
1111
HLQGP
1116
VSMGL
1121
GDMQP
1126
SLNPP
1131
KVGSA
1136
SLSSG
1141
RLHKR
1146
KHKHK
1151
HKHKE
1156
DRILG
1161
THDNL
1166
SGLFA
1171
GKATG
1176
FSSHI
1181
LSERL
1186
SSADK
1191
ELPLV
1196
SEKNK
1201
HKEKQ
1206
KHQHS
1211
EAGHK
1216
ASKNN
1221
FEVDT
1226
LSTLS
1231
LSDAQ
1236
HWTQA
1241
KEKGD
1246
LSSEP
1251
VDSCT
1256
KRYSG
1261
SGGDG
1266
GSTRS
1271
ENLDV
1276
FSEMN
1281
PSNDK
1286
WDSDV
1291
SGSKR
1296
RSYEG
1301
FGTYR
1306
EKDIQ
1311
AFKMN
1316
RKERS
1321
SYDSS
1326
MSPGM
1331
PSPHL
1336
KVDQT
1341
AVHSK
1346
NEGSV
1351
PTMMT
1356
RKKPA
1361
AVDSV
1366
TIPPA
1371
PVLSL
1376
LAASA
1381
ATSDA
1386
VGSSL
1391
KKRFK
1396
RREIE
1401
AIQCE
1406
VRKMC
1411
NYTKI
1416
LSTKK
1421
NLDHV
1426
NKILK
1431
AKRLQ
1436
RQSKT
1441
GNNFV
1446
KKRRG
1451
RPRKQ
1456
PTQFD
1461
EDSRD
1466
QMPVL
1471
EKCID
1476
LPSKR
1481
GQKPS
1486
LSPLV
1491
LEPAA
1496
SQDTI
1501
MATIE
1506
AVIHM
1511
AREAP
1516
PLPPP
1521
PPPPL
1526
PPPPP
1531
PPLPP
1536
PPPLP
1541
KTPRG
1546
GKRKH
1551
KPQAP
1556
AQPPQ
1561
QSPPQ
1566
QPLPQ
1571
EEEVK
1576
AKRQR
1581
KSRGS
1586
ESEVL
1591
P
1596
Mutation Information
DNA mutation:
None
Peptide Range:
1077 ~ 1098
Mut AA position:
1084 (8 in Wild Type peptide)
Alignment
Wild Type:
"---HTLGAASPF----------
|||||||.|
Mutant:
YLSHTLGAASSFMRPTVPPPQF"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) SETBP1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay