Immunogenicity 4175

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
LPAR4
Transcript ID
uc031tjz.1
HLA INFO
A*11:01
TCR INFO

No TCR info found!

T cell Tumor cell A*11:01
sequence
Full length protein sequence (370 aa)
MGDRR
1
FIDFQ
6
FQDSN
11
SSLRP
16
RLGNA
21
TANNT
26
CIVDD
31
SFKYN
36
LNGAV
41
YSVVF
46
ILGLI
51
TNSVS
56
LFVFC
61
FRMKM
66
RSETA
71
IFITN
76
LAVSD
81
LLFVC
86
TLPFK
91
IFYNF
96
NRHWP
101
FGDTL
106
CKISG
111
TAFLT
116
NIYGS
121
MLFLT
126
CISVD
131
RFLAI
136
VYPFR
141
SRTIR
146
TRRNS
151
AIVCA
156
GVWIL
161
VLSGG
166
ISASL
171
FSTTN
176
VNNAT
181
TTCFE
186
GFSKR
191
VWKTY
196
LSKIT
201
IFIEV
206
VGFII
211
PLILN
216
VSCSS
221
VVLRT
226
LRKPA
231
TLSQI
236
GTNKK
241
KVLKM
246
ITVHM
251
AVFVV
256
CFVPY
261
NSVLF
266
LYALV
271
RSQAI
276
TNCFL
281
ERFAK
286
IMYPI
291
TLCLA
296
TLNCC
301
FDPFI
306
YYFTL
311
ESFQK
316
SFYIN
321
AHIRM
326
ESLFK
331
TETPL
336
TTKPS
341
LPAIQ
346
EEVSD
351
QTTNN
356
GGELM
361
LESTF
366
Mutation Information
DNA mutation:
None
Peptide Range:
160 ~ 183
Mut AA position:
172 (13 in Wild Type peptide)
Alignment
Wild Type:
"AGVWILVLSGGISASLFSTTNVNN
||||||||||||.|||||||||||
Mutant:
AGVWILVLSGGILASLFSTTNVNN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LPAR4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay