Immunogenicity 4182

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
UBE2DNL
Transcript ID
uc011mqw.2
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (210 aa)
MWAVG
1
ASRWG
6
RLPPA
11
RGAAA
16
PNHKI
21
SNAGQ
26
RGLGH
31
HTLQA
36
SCRPS
41
RVVER
46
PALIV
51
VSPPL
56
RHRPI
61
PPTPP
66
PTPEL
71
ALSPF
76
ICRGI
81
PLLPI
86
PPRDR
91
HLCPL
96
PGSGP
101
GAEDW
106
PPRVA
111
DYGPK
116
AHPQG
121
VPRTG
126
PRPPA
131
PLLSR
136
ASVGR
141
YAPLA
146
GHHNE
151
AQRQL
156
LPGRG
161
LLPKV
166
SLRLP
171
IQTTQ
176
DQIYQ
181
RNLPS
186
TLTEI
191
RDRRE
196
YGRIA
201
KDWTQ
206
Mutation Information
DNA mutation:
None
Peptide Range:
52 ~ 76
Mut AA position:
64 (13 in Wild Type peptide)
Alignment
Wild Type:
"ALIVVSPPLRHRPIPPTPPPTPELA
||||||||||||.||||||||||||
Mutant:
ALIVVSPPLRHRLIPPTPPPTPELA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UBE2DNL

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay