Immunogenicity 419

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DNMT3A
Transcript ID
None
HLA INFO
B*08:01
TCR INFO

No TCR info found!

T cell Tumor cell B*08:01
sequence
Full length protein sequence (912 aa)
MPAMP
1
SSGPG
6
DTSSS
11
AAERE
16
EDRKD
21
GEEQE
26
EPRGK
31
EERQE
36
PSTTA
41
RKVGR
46
PGRKR
51
KHPPV
56
ESGDT
61
PKDPA
66
VISKS
71
PSMAQ
76
DSGAS
81
ELLPN
86
GDLEK
91
RSEPQ
96
PEEGS
101
PAGGQ
106
KGGAP
111
AEGEG
116
AAETL
121
PEASR
126
AVENG
131
CCTPK
136
EGRGA
141
PAEAG
146
KEQKE
151
TNIES
156
MKMEG
161
SRGRL
166
RGGLG
171
WESSL
176
RQRPM
181
PRLTF
186
QAGDP
191
YYISK
196
RKRDE
201
WLARW
206
KREAE
211
KKAKV
216
IAGMN
221
AVEEN
226
QGPGE
231
SQKVE
236
EASPP
241
AVQQP
246
TDPAS
251
PTVAT
256
TPEPV
261
GSDAG
266
DKNAT
271
KAGDD
276
EPEYE
281
DGRGF
286
GIGEL
291
VWGKL
296
RGFSW
301
WPGRI
306
VSWWM
311
TGRSR
316
AAEGT
321
RWVMW
326
FGDGK
331
FSVVC
336
VEKLM
341
PLSSF
346
CSAFH
351
QATYN
356
KQPMY
361
RKAIY
366
EVLQV
371
ASSRA
376
GKLFP
381
VCHDS
386
DESDT
391
AKAVE
396
VQNKP
401
MIEWA
406
LGGFQ
411
PSGPK
416
GLEPP
421
EEEKN
426
PYKEV
431
YTDMW
436
VEPEA
441
AAYAP
446
PPPAK
451
KPRKS
456
TAEKP
461
KVKEI
466
IDERT
471
RERLV
476
YEVRQ
481
KCRNI
486
EDICI
491
SCGSL
496
NVTLE
501
HPLFV
506
GGMCQ
511
NCKNC
516
FLECA
521
YQYDD
526
DGYQS
531
YCTIC
536
CGGRE
541
VLMCG
546
NNNCC
551
RCFCV
556
ECVDL
561
LVGPG
566
AAQAA
571
IKEDP
576
WNCYM
581
CGHKG
586
TYGLL
591
RRRED
596
WPSRL
601
QMFFA
606
NNHDQ
611
EFDPP
616
KVYPP
621
VPAEK
626
RKPIR
631
VLSLF
636
DGIAT
641
GLLVL
646
KDLGI
651
QVDRY
656
IASEV
661
CEDSI
666
TVGMV
671
RHQGK
676
IMYVG
681
DVRSV
686
TQKHI
691
QEWGP
696
FDLVI
701
GGSPC
706
NDLSI
711
VNPAR
716
KGLYE
721
GTGRL
726
FFEFY
731
RLLHD
736
ARPKE
741
GDDRP
746
FFWLF
751
ENVVA
756
MGVSD
761
KRDIS
766
RFLES
771
NPVMI
776
DAKEV
781
SAAHR
786
ARYFW
791
GNLPG
796
MNRPL
801
ASTVN
806
DKLEL
811
QECLE
816
HGRIA
821
KFSKV
826
RTITT
831
RSNSI
836
KQGKD
841
QHFPV
846
FMNEK
851
EDILW
856
CTEME
861
RVFGF
866
PVHYT
871
DVSNM
876
SRLAR
881
QRLLG
886
RSWSV
891
PVIRH
896
LFAPL
901
KEYFA
906
CV
911
Mutation Information
DNA mutation:
None
Peptide Range:
863 ~ 884
Mut AA position:
865 (3 in Wild Type peptide)
Alignment
Wild Type:
"---EMERVFGFPV---------
||.|||||||
Mutant:
WCTEMKRVFGFPVHYTDVSNMS"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) DNMT3A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay