Immunogenicity 42

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
SRRM2
Transcript ID
uc010bsu.1
HLA INFO
A*24:01
TCR INFO

No TCR info found!

T cell Tumor cell A*24:01
sequence
Full length protein sequence (2751 aa)
MYNGI
1
GLPTP
6
RGSGT
11
NGYVQ
16
RNLSL
21
VRGRR
26
GERPD
31
YKGEE
36
ELRRL
41
EAALV
46
KRPNP
51
DILDH
56
ERKRR
61
VELRC
66
LELEE
71
MMEEQ
76
GYEEQ
81
QIQEK
86
VATFR
91
LMLLE
96
KDVNP
101
GGKEE
106
TPGQR
111
PAVTE
116
THQLA
121
ELNEK
126
KNERL
131
RAAFG
136
ISDSY
141
VDGSS
146
FDPQR
151
RAREA
156
KQPAP
161
EPPKP
166
YSLVR
171
ESSSS
176
RSPTP
181
KQKKK
186
KKKKD
191
RGRRS
196
ESSSP
201
RRERK
206
KSSKK
211
KKHRS
216
ESESK
221
KRKHR
226
SPTPK
231
SKRKS
236
KDKKR
241
KRSRS
246
TTPAP
251
KSRRA
256
HRSTS
261
ADSAS
266
SSDTS
271
RSRSR
276
SAAAK
281
THTTA
286
LAGRS
291
PSPAS
296
GRRGE
301
GDAPF
306
SEPGT
311
TSTQR
316
PSSPE
321
TATKQ
326
PSSPY
331
EDKDK
336
DKKEK
341
SATRP
346
SPSPE
351
RSSTG
356
PEPPA
361
PTPLL
366
AERHG
371
GSPQP
376
LATTP
381
LSQEP
386
VNPPS
391
EASPT
396
RDRSP
401
PKSPE
406
KLPQS
411
SSSES
416
SPPSP
421
QPTKV
426
SRHAS
431
SSPES
436
PKPAP
441
APGSH
446
REISS
451
SPTSK
456
NRSHG
461
RAKRD
466
KSHSH
471
TPSRR
476
MGRSR
481
SPATA
486
KRGRS
491
RSRTP
496
TKRGH
501
SRSRS
506
PQWRR
511
SRSAQ
516
RWGRS
521
RSPQR
526
RGRSR
531
SPQRP
536
GWSRS
541
RNTQR
546
RGRSR
551
SARRG
556
RSHSR
561
SPATR
566
GRSRS
571
RTPAR
576
RGRSR
581
SRTPA
586
RRRSR
591
SRTPT
596
RRRSR
601
SRTPA
606
RRGRS
611
RSRTP
616
ARRRS
621
RTRSP
626
VRRRS
631
RSRSP
636
ARRSG
641
RSRSR
646
TPARR
651
GRSRS
656
RTPAR
661
RGRSR
666
SRTPA
671
RRSGR
676
SRSRT
681
PARRG
686
RSRSR
691
TPRRG
696
RSRSR
701
SLVRR
706
GRSHS
711
RTPQR
716
RGRSG
721
SSSER
726
KNKSR
731
TSQRR
736
SRSNS
741
SPEMK
746
KSRIS
751
SRRSR
756
SLSSP
761
RSKAK
766
SRLSL
771
RRSLS
776
GSSPC
781
PKQKS
786
QTPPR
791
RSRSG
796
SSQPK
801
AKSRT
806
PPRRS
811
RSSSS
816
PPPKQ
821
KSKTP
826
SRQSH
831
SSSSP
836
HPKVK
841
SGTPP
846
RQGSI
851
TSPQA
856
NEQSV
861
TPQRR
866
SCFES
871
SPDPE
876
LKSRT
881
PSRHS
886
CSGSS
891
PPRVK
896
SSTPP
901
RQSPS
906
RSSSP
911
QPKVK
916
AIISP
921
RQRSH
926
SGSSS
931
PSPSR
936
VTSRT
941
TPRRS
946
RSVSP
951
CSNVE
956
SRLLP
961
RYSHS
966
GSSSP
971
DTKVK
976
PETPP
981
RQSHS
986
GSISP
991
YPKVK
996
AQTPP
1001
GPSLS
1006
GSKSP
1011
CPQEK
1016
SKDSL
1021
VQSCP
1026
GSLSL
1031
CAGVK
1036
SSTPP
1041
GESYF
1046
GVSSL
1051
QLKGQ
1056
SQTSP
1061
DHRSD
1066
TSSPE
1071
VRQSH
1076
SESPS
1081
LQSKS
1086
QTSPK
1091
GGRSR
1096
SSSPV
1101
TELAS
1106
RSPIR
1111
QDRGE
1116
FSASP
1121
MLKSG
1126
MSPEQ
1131
SRFQS
1136
DSSSY
1141
PTVDS
1146
NSLLG
1151
QSRLE
1156
TAESK
1161
EKMAL
1166
PPQED
1171
ATASP
1176
PRQKD
1181
KFSPF
1186
PVQDR
1191
PESSL
1196
VFKDT
1201
LRTPP
1206
RERSG
1211
AGSSP
1216
ETKEQ
1221
NSALP
1226
TSSQD
1231
EELME
1236
VVEKS
1241
EEPAG
1246
QILSH
1251
LSSEL
1256
KEMST
1261
SNFES
1266
SPEVE
1271
ERPAV
1276
SLTLD
1281
QSQSQ
1286
ASLEA
1291
VEVPS
1296
MASSW
1301
GGPHF
1306
SPEHK
1311
ELSNS
1316
PLREN
1321
SFGSP
1326
LEFRN
1331
SGPLG
1336
TEMNT
1341
GFSSE
1346
VKEDL
1351
NGPFL
1356
NQLET
1361
DPSLD
1366
MKEQS
1371
TRSSG
1376
HSSSE
1381
LSPDA
1386
VEKAG
1391
MSSNQ
1396
SISSP
1401
VLDAV
1406
PRTPS
1411
RERSS
1416
SASSP
1421
EMKDG
1426
LPRTP
1431
SRRSR
1436
SGSSP
1441
GLRDG
1446
SGTPS
1451
RHSLS
1456
GSSPG
1461
MKDIP
1466
RTPSR
1471
GRSEC
1476
DSSPE
1481
PKALP
1486
QTPRP
1491
RSRSP
1496
SSPEL
1501
NNKCL
1506
TPQRE
1511
RSGSE
1516
SSVDQ
1521
KTVAR
1526
TPLGQ
1531
RSRSG
1536
SSQEL
1541
DVKPS
1546
ASPQE
1551
RSESD
1556
SSPDS
1561
KAKTR
1566
TPLRQ
1571
RSRSG
1576
SSPEV
1581
DSKSR
1586
LSPRR
1591
SRSGS
1596
SPEVK
1601
DKPRA
1606
APRAQ
1611
SGSDS
1616
SPEPK
1621
APAPR
1626
ALPRR
1631
SRSGS
1636
SSKGR
1641
GPSPE
1646
GSSST
1651
ESSPE
1656
HPPKS
1661
RTARR
1666
GSRSS
1671
PEPKT
1676
KSRTP
1681
PRRRS
1686
SRSSP
1691
ELTRK
1696
ARLSR
1701
RSRSA
1706
SSSPE
1711
TRSRT
1716
PPRHR
1721
RSPSV
1726
SSPEP
1731
AEKSR
1736
SSRRR
1741
RSASS
1746
PRTKT
1751
TSRRG
1756
RSPSP
1761
KPRGL
1766
QRSRS
1771
RSRRE
1776
KTRTT
1781
RRRDR
1786
SGSSQ
1791
STSRR
1796
RQRSR
1801
SRSRV
1806
TRRRR
1811
GGSGY
1816
HSRSP
1821
ARQES
1826
SRTSS
1831
RRRRG
1836
RSRTP
1841
PTSRK
1846
RSRSR
1851
TSPAP
1856
WKRSR
1861
SRASP
1866
ATHRR
1871
SRSRT
1876
PLISR
1881
RRSRS
1886
RTSPV
1891
SRRRS
1896
RSRTS
1901
VTRRR
1906
SRSRA
1911
SPVSR
1916
RRSRS
1921
RTPPV
1926
TRRRS
1931
RSRTP
1936
TTRRR
1941
SRSRT
1946
PPVTR
1951
RRSRS
1956
RTPPV
1961
TRRRS
1966
RSRTS
1971
PITRR
1976
RSRSR
1981
TSPVT
1986
RRRSR
1991
SRTSP
1996
VTRRR
2001
SRSRT
2006
SPVTR
2011
RRSRS
2016
RTPPA
2021
IRRRS
2026
RSRTP
2031
LLPRK
2036
RSRSR
2041
SPLAI
2046
RRRSR
2051
SRTPR
2056
TARGK
2061
RSLTR
2066
SPPAI
2071
RRRSA
2076
SGSSS
2081
DRSRS
2086
ATPPA
2091
TRNHS
2096
GSRTP
2101
PVALN
2106
SSRMS
2111
CFSRP
2116
SMSPT
2121
PLDRC
2126
RSPGM
2131
LEPLG
2136
SSRTP
2141
MSVLQ
2146
QAGGS
2151
MMDGP
2156
GPRIP
2161
DHQRT
2166
SVPEN
2171
HAQSR
2176
IALAL
2181
TAISL
2186
GTARP
2191
PPSMS
2196
AAGLA
2201
ARMSQ
2206
VPAPV
2211
PLMSL
2216
RTAPA
2221
ANLAS
2226
RIPAA
2231
SAAAM
2236
NLASA
2241
RTPAI
2246
PTAVN
2251
LADSR
2256
TPAAA
2261
AAMNL
2266
ASPRT
2271
AVAPS
2276
AVNLA
2281
DPRTP
2286
TAPAV
2291
NLAGA
2296
RTPAA
2301
LAALS
2306
LTGSG
2311
TPPTA
2316
ANYPS
2321
SSRTP
2326
QAPAS
2331
ANLVG
2336
PRSAH
2341
ATAPV
2346
NIAGS
2351
RTAAA
2356
LAPAS
2361
LTSAR
2366
MAPAL
2371
SGANL
2376
TSPRV
2381
PLSAY
2386
ERVSG
2391
RTSPP
2396
LLDRA
2401
RSRTP
2406
PSAPS
2411
QSRMT
2416
SERAP
2421
SPSSR
2426
MGQAP
2431
SQSLL
2436
PPAQD
2441
QPRSP
2446
VPSAF
2451
SDQSR
2456
CLIAQ
2461
TTPVA
2466
GSQSL
2471
SSGAV
2476
ATTTS
2481
SAGDH
2486
NGMLS
2491
VPAPG
2496
VPHSD
2501
VGEPP
2506
ASTGA
2511
QQPSA
2516
LAALQ
2521
PAKER
2526
RSSSS
2531
SSSSS
2536
SSSSS
2541
SSSSS
2546
SSSSS
2551
SGSSS
2556
SDSEG
2561
SSLPV
2566
QPEVA
2571
LKRVP
2576
SPTPA
2581
PKEAV
2586
REGRP
2591
PEPTP
2596
AKRKR
2601
RSSSS
2606
SSSSS
2611
SSSSS
2616
SSSSS
2621
SSSSS
2626
SSSSS
2631
SSSSS
2636
SSSSS
2641
SSSPS
2646
PAKPG
2651
PQALP
2656
KPASP
2661
KKPPP
2666
GERRS
2671
RSPRK
2676
PIDSL
2681
RDSRS
2686
LSYSP
2691
VERRR
2696
PSPQP
2701
SPRDQ
2706
QSSSE
2711
RGSRR
2716
GQRGD
2721
SRSPS
2726
HKRRR
2731
ETPSP
2736
RPMRH
2741
RSSRS
2746
P
2751
Mutation Information
DNA mutation:
c.T6362C
Peptide Range:
2205 ~ 2229
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"AARMSQVPAPVPLMSLRTAPAANLA
||||||||||||.||||||||||||
Mutant:
AARMSQVPAPVPPMSLRTAPAANLA"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

AARMSQVPAPVPPMSLRTAPAANLA

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT