Immunogenicity 4216

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
NKAP
Transcript ID
uc004esh.3
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (415 aa)
MAPVS
1
GSRSP
6
DREAS
11
GSGGR
16
RRSSS
21
KSPKP
26
SKSAR
31
SPRGR
36
RSRSH
41
SCSRS
46
GDRNG
51
LTHQL
56
GGLSQ
61
GSRNQ
66
SYRSR
71
SRSRS
76
RERPS
81
APRGI
86
PFASA
91
SSSVY
96
YGSYS
101
RPYGS
106
DKPWP
111
SLLDK
116
EREES
121
LRQKR
126
LSERE
131
RIGEL
136
GAPEV
141
WGLSP
146
KNPEP
151
DSDEH
156
TPVED
161
EEPKK
166
STTSA
171
STSEE
176
EKKKK
181
SSRSK
186
ERSKK
191
RRKKK
196
SSKRK
201
HKKYS
206
EDSDS
211
DSDSE
216
TDSSD
221
EDNKR
226
RAKKA
231
KKKEK
236
KKKHR
241
SKKYK
246
KKRSK
251
KSRKE
256
SSDSS
261
SKESQ
266
EEFLE
271
NPWKD
276
RTKAE
281
EPSDL
286
IGPEA
291
PKTLT
296
SQDDK
301
PLNYG
306
HALLP
311
GEGAA
316
MAEYV
321
KAGKR
326
IPRRG
331
EIGLT
336
SEEIA
341
SFECS
346
GYVMS
351
GSRHR
356
RMEAV
361
RLRKE
366
NQIYS
371
ADEKR
376
ALASF
381
NQEER
386
RKREN
391
KILAS
396
FREMV
401
YRKTK
406
GKDDK
411
Mutation Information
DNA mutation:
None
Peptide Range:
234 ~ 258
Mut AA position:
246 (13 in Wild Type peptide)
Alignment
Wild Type:
"KAKKKEKKKKHRSKKYKKKRSKKSR
||||||||||||.||||||||||||
Mutant:
KAKKKEKKKKHRTKKYKKKRSKKSR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NKAP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay