Immunogenicity 4222

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MAGEC1
Transcript ID
uc022cfi.1
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (801 aa)
MTSSF
1
SSTLL
6
SIFQS
11
SPESA
16
QSTFE
21
GFPQS
26
PLQIP
31
GSPSF
36
SSTLL
41
SLFQS
46
SPERT
51
HSTFE
56
GFPQS
61
PLQIP
66
MTSSF
71
SSTLL
76
SILQS
81
SPESA
86
QSAFE
91
GFPQS
96
PLQIP
101
VSSSF
106
SYTLL
111
SLFQS
116
SPERT
121
HSTFE
126
GFPQS
131
PLQIP
136
VSSSS
141
SSSTL
146
LSLFQ
151
SSPEC
156
TQSTF
161
EGFPQ
166
SPLQI
171
PQSPP
176
EGENT
181
HSPLQ
186
IVPSL
191
PEWED
196
SLSPH
201
YFPQS
206
PPQGE
211
DSLSP
216
HYFPQ
221
SPPQG
226
EDSLS
231
PHYFP
236
QSPQG
241
EDSLS
246
PHYFP
251
QSPPQ
256
GEDSM
261
SPLYF
266
PQSPL
271
QGEEF
276
QSSLQ
281
SPVSI
286
CSSST
291
PSSLP
296
QSFPE
301
SSQSP
306
PEGPV
311
QSPLH
316
SPQSP
321
PEGMH
326
SQSPL
331
QSPES
336
APEGE
341
DSLSP
346
LQIPQ
351
SPLEG
356
EDSLS
361
SLHFP
366
QSPPE
371
WEDSL
376
SPLHF
381
PQFPP
386
QGEDF
391
QSSLQ
396
SPVSI
401
CSSST
406
SLSLP
411
QSFPE
416
SPQSP
421
PEGPA
426
QSPLQ
431
RPVSS
436
FFSYT
441
LASLL
446
QSSHE
451
SPQSP
456
PEGPA
461
QSPLQ
466
SPVSS
471
FPSST
476
SSSLS
481
QSSPV
486
SSFPS
491
STSSS
496
LSKSS
501
PESPL
506
QSPVI
511
SFSSS
516
TSLSP
521
FSEES
526
SSPVD
531
EYTSS
536
SDTLL
541
ESDSL
546
TDSES
551
LIESE
556
PLFTY
561
TLDEK
566
VDELA
571
RFLLL
576
KYQVK
581
QPITK
586
AEMLT
591
NVISR
596
YTGYF
601
PVIFR
606
KAREF
611
IEILF
616
GISLR
621
EVDPD
626
DSYVF
631
VNTLD
636
LTSEG
641
CLSDE
646
QGMSQ
651
NRLLI
656
LILSI
661
IFIKG
666
TYASE
671
EVIWD
676
VLSGI
681
GVRAG
686
REHFA
691
FGEPR
696
ELLTK
701
VWVQE
706
HYLEY
711
REVPN
716
SSPPR
721
YEFLW
726
GPRAH
731
SEVIK
736
RKVVE
741
FLAML
746
KNTVP
751
ITFPS
756
SYKDA
761
LKDVE
766
ERAQA
771
IIDTT
776
DDSTA
781
TESAS
786
SSVMS
791
PSFSS
796
E
801
Mutation Information
DNA mutation:
None
Peptide Range:
618 ~ 642
Mut AA position:
630 (13 in Wild Type peptide)
Alignment
Wild Type:
"ILFGISLREVDPDDSYVFVNTLDLT
||||||||||||.||||||||||||
Mutant:
ILFGISLREVDPEDSYVFVNTLDLT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MAGEC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay