Immunogenicity 424
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CASC1
Transcript ID
None
HLA INFO
B*41:02
TCR INFO
No TCR info found!
Full length protein sequence (616 aa)
MGPKA
1
KKSGS
6
KKKKV
11
TKAER
16
LKLLQ
21
EEEER
26
RLKEE
31
EEARL
36
KYEKE
41
EMERL
46
EIQRI
51
EKEKW
56
HRLEA
61
KDLER
66
RNEEL
71
EELYL
76
LERCF
81
PEAEK
86
LKQET
91
KLLSQ
96
WKHYI
101
QCDGS
106
PDPSV
111
AQEMN
116
TFISL
121
WKEKT
126
NETFE
131
EVIEK
136
SKVVL
141
NLIEK
146
LKFIL
151
LETPP
156
CDLQD
161
KNIIQ
166
YQESI
171
LQLQE
176
LLHLK
181
FGVAT
186
EILLK
191
QASTL
196
ADLDS
201
GNMEK
206
VIKDE
211
NVTLY
216
VWANL
221
KKNPR
226
HRSVR
231
FSETQ
236
IGFEI
241
PRILA
246
TSDIA
251
VRLLH
256
THYDH
261
VSALH
266
PVSTP
271
SKEYT
276
SAVTE
281
LVKDD
286
VKNVE
291
KAISK
296
EVEEE
301
SKQQE
306
RGSHL
311
IQEEE
316
IKVEE
321
EQGDI
326
EVKMS
331
SAEEE
336
SEAIK
341
CEREM
346
KVLSE
351
TVSAG
356
KHWRT
361
DGISN
366
VSYKP
371
KERLV
376
TFSLD
381
TFGPV
386
TLIQD
391
AHINM
396
PYQSW
401
ELRPL
406
DVNKV
411
LLTVT
416
TVFTE
421
IQIQI
426
KENLC
431
MLSSI
436
KLKDK
441
KHISI
446
LEGTW
451
MTPIP
456
FIIAL
461
KEAGL
466
NIFPT
471
RHSHF
476
YVIIN
481
NKVPL
486
VEVKA
491
YRQMA
496
LLSSA
501
FAFGW
506
SKWNL
511
LCNST
516
KVVFK
521
VREHL
526
TEECT
531
ENPNW
536
ALLMF
541
SGDRA
546
QRLKI
551
KEESE
556
AFSEA
561
LKEET
566
EFHST
571
LYHMV
576
KDFAS
581
EEAME
586
KVRSS
591
NCQFV
596
NSVCH
601
MLLST
606
RLLSY
611
S
616
Mutation Information
DNA mutation:
None
Peptide Range:
263 ~ 286
Mut AA position:
265 (3 in Wild Type peptide)
Alignment
Wild Type:
"----YDHVSALHPV----------
||.|||||||
Mutant:
LHTHYDYVSALHPVSTPSKEYTSA"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) CASC1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay