Immunogenicity 427
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MAP4K4
Transcript ID
None
HLA INFO
B*35:01
TCR INFO
No TCR info found!
Full length protein sequence (1384 aa)
MANDS
1
PAKSL
6
VDIDL
11
SSLRD
16
PAGIF
21
ELVEV
26
VGNGT
31
YGQVY
36
KGRHV
41
KTGQL
46
AAIKV
51
MDVTE
56
DEEEE
61
IKLEI
66
NMLKK
71
YSHHR
76
NIATY
81
YGAFI
86
KKSPP
91
GHDDQ
96
LWLVM
101
EFCGA
106
GSITD
111
LVKNT
116
KGNTL
121
KEDWI
126
AYISR
131
EILRG
136
LAHLH
141
IHHVI
146
HRDIK
151
GQNVL
156
LTENA
161
EVKLV
166
DFGVS
171
AQLDR
176
TVGRR
181
NTFIG
186
TPYWM
191
APEVI
196
ACDEN
201
PDATY
206
DYRSD
211
LWSCG
216
ITAIE
221
MAEGA
226
PPLCD
231
MHPMR
236
ALFLI
241
PRNPP
246
PRLKS
251
KKWSK
256
KFFSF
261
IEGCL
266
VKNYM
271
QRPST
276
EQLLK
281
HPFIR
286
DQPNE
291
RQVRI
296
QLKDH
301
IDRTR
306
KKRGE
311
KDETE
316
YEYSG
321
SEEEE
326
EEVPE
331
QEGEP
336
SSIVN
341
VPGES
346
TLRRD
351
FLRLQ
356
QENKE
361
RSEAL
366
RRQQL
371
LQEQQ
376
LREQE
381
EYKRQ
386
LLAER
391
QKRIE
396
QQKEQ
401
RRRLE
406
EQQRR
411
EREAR
416
RQQER
421
EQRRR
426
EQEEK
431
RRLEE
436
LERRR
441
KEEEE
446
RRRAE
451
EEKRR
456
VEREQ
461
EYIRR
466
QLEEE
471
QRHLE
476
VLQQQ
481
LLQEQ
486
AMLLE
491
CRWRE
496
MEEHR
501
QAERL
506
QRQLQ
511
QEQAY
516
LLSLQ
521
HDHRR
526
PHPQH
531
SQQPP
536
PPQQE
541
RSKPS
546
FHAPE
551
PKAHY
556
EPADR
561
AREVE
566
DRFRK
571
TNHSS
576
PEAQS
581
KQTGR
586
VLEPP
591
VPSRS
596
ESFSN
601
GNSES
606
VHPAL
611
QRPAE
616
PQVQW
621
SHLAS
626
LKNNV
631
SPVSR
636
SHSFS
641
DPSPK
646
FAHHH
651
LRSQD
656
PCPPS
661
RSEVL
666
SQSSD
671
SKSEA
676
PDPTQ
681
KAWSR
686
SDSDE
691
VPPRV
696
PVRTT
701
SRSPV
706
LSRRD
711
SPLQG
716
SGQQN
721
SQAGQ
726
RNSTS
731
SIEPR
736
LLWER
741
VEKLV
746
PRPGS
751
GSSSG
756
SSNSG
761
SQPGS
766
HPGSQ
771
SGSGE
776
RFRVR
781
SSSKS
786
EGSPS
791
QRLEN
796
AVKKP
801
EDKKE
806
VFRPL
811
KPAGE
816
VDLTA
821
LAKEL
826
RAVED
831
VRPPH
836
KVTDY
841
SSSSE
846
ESGTT
851
DEEDD
856
DVEQE
861
GADES
866
TSGPE
871
DTRAA
876
SSLNL
881
SNGET
886
ESVKT
891
MIVHD
896
DVESE
901
PAMTP
906
SKEGT
911
LIVRQ
916
STVDQ
921
KRASH
926
HESNG
931
FAGRI
936
HLLPD
941
LLQQS
946
HSSST
951
SSTSS
956
SPSSS
961
QPTPT
966
MSPQT
971
PQDKL
976
TANET
981
QSASS
986
TLQKH
991
KSSSS
996
FTPFI
1001
DPRLL
1006
QISPS
1011
SGTTV
1016
TSVVG
1021
FSCDG
1026
MRPEA
1031
IRQDP
1036
TRKGS
1041
VVNVN
1046
PTNTR
1051
PQSDT
1056
PEIRK
1061
YKKRF
1066
NSEIL
1071
CAALW
1076
GVNLL
1081
VGTES
1086
GLMLL
1091
DRSGQ
1096
GKVYP
1101
LINRR
1106
RFQQM
1111
DVLEG
1116
LNVLV
1121
TISGK
1126
KDKLR
1131
VYYLS
1136
WLRNK
1141
ILHND
1146
PEVEK
1151
KQGWT
1156
TVGDL
1161
EGCVH
1166
YKVVK
1171
YERIK
1176
FLVIA
1181
LKSSV
1186
EVYAW
1191
APKPY
1196
HKFMA
1201
FKSFG
1206
ELVHK
1211
PLLVD
1216
LTVEE
1221
GQRLK
1226
VIYGS
1231
CAGFH
1236
AVDVD
1241
SGSVY
1246
DIYLP
1251
THIQC
1256
SIKPH
1261
AIIIL
1266
PNTDG
1271
MELLV
1276
CYEDE
1281
GVYVN
1286
TYGRI
1291
TKDVV
1296
LQWGE
1301
MPTSV
1306
AYIRS
1311
NQTMG
1316
WGEKA
1321
IEIRS
1326
VETGH
1331
LDGVF
1336
MHKRA
1341
QRLKF
1346
LCERN
1351
DKVFF
1356
ASVRS
1361
GGSSQ
1366
VYFMT
1371
LGRTS
1376
LLSW
1381
Mutation Information
DNA mutation:
None
Peptide Range:
636 ~ 662
Mut AA position:
639 (4 in Wild Type peptide)
Alignment
Wild Type:
"----------SPVSRSHSF--------
|||.|||||
Mutant:
SHLASLKNNVSPVLRSHSFSDPSPKFA"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) MAP4K4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay