Immunogenicity 429
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
NCOA6
Transcript ID
None
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (2056 aa)
MVLDD
1
LPNLE
6
DIYTS
11
LCSST
16
MEDSE
21
MDFDS
26
GLEDD
31
DTKSD
36
SILED
41
STIFV
46
AFKGN
51
IDDKD
56
FKWKL
61
DAILK
66
NVPNL
71
LHMES
76
SKLKV
81
QKVEP
86
WNSVR
91
VTFNI
96
PREAA
101
ERLRI
106
LAQSN
111
NQQLR
116
DLGIL
121
SVQIE
126
GEGAI
131
NLALA
136
QNRSQ
141
DVRMN
146
GPMGA
151
GNSVR
156
MEAGF
161
PMASG
166
PGIFF
171
LGIIR
176
MNNPA
181
TVMIP
186
PGGNV
191
SSSMM
196
APGPN
201
PELQP
206
RTPRP
211
ASQSD
216
AMDPL
221
LSGLH
226
IQQQS
231
HPSGS
236
LAPPH
241
HPMQP
246
VSVNR
251
QMNPA
256
NFPQL
261
QQQQQ
266
QQQQQ
271
QQQQQ
276
QQQQQ
281
QQQQQ
286
LQARP
291
PQQHQ
296
QQQPQ
301
GIRPQ
306
FTAPT
311
QVPVP
316
PGWNQ
321
LPSGA
326
LQPPP
331
AQGSL
336
GTMTA
341
NQGWK
346
KAPLP
351
GPMQQ
356
QLQAR
361
PSLAT
366
VQTPS
371
HPPPP
376
YPFGS
381
QQASQ
386
AHTNF
391
PQMSN
396
PGQFT
401
APQMK
406
SLQGG
411
PSRVP
416
TPLQQ
421
PHLTN
426
KSPAS
431
SPSSF
436
QQGSP
441
ASSPT
446
VNQTQ
451
QQMGP
456
RPPQN
461
NPLPQ
466
GFQQP
471
VSSPG
476
RNPMV
481
QQGNV
486
PPNFM
491
VMQQQ
496
PPNQG
501
PQSLH
506
PGLGG
511
QANPN
516
FMQGQ
521
VPSTT
526
ATTPG
531
NSGAP
536
QLQAN
541
QNVQH
546
AGGQG
551
AGPPQ
556
NQMQV
561
SHGPP
566
NMMQP
571
SLMGI
576
HGNMN
581
NQQAG
586
TSGVP
591
QVNLS
596
NMQGQ
601
PQQGP
606
PSQLM
611
GMHQQ
616
IVPSQ
621
GQMVQ
626
QQGTL
631
NPQNP
636
MILSR
641
AQLMP
646
QGQMM
651
VNPPS
656
QNLGP
661
SPQRM
666
TPPKQ
671
MLSQQ
676
GPQMM
681
APHNQ
686
MMGPQ
691
GQVLL
696
QQNPM
701
IEQIM
706
TNQMQ
711
GNKQQ
716
FNTQN
721
QSNVM
726
PGPAQ
731
IMRGP
736
TPNMQ
741
GNMVQ
746
FTGQM
751
SGQML
756
PQQGP
761
VNNSP
766
SQVMG
771
IQGQV
776
LRPPG
781
PSPHM
786
AQQHG
791
DPATT
796
ANNDV
801
SLSQM
806
MPDVS
811
IQQTN
816
MVPPH
821
VQAMQ
826
GNSAS
831
GNHFS
836
GHGMS
841
FNAPF
846
SGAPN
851
GNQMS
856
CGQNP
861
GFPVN
866
KDVTL
871
TSPLL
876
VNLLQ
881
SDISA
886
GHFGV
891
NNKQN
896
NTNAN
901
KPKKK
906
KPPRK
911
KKNSQ
916
QDLNT
921
PDTRP
926
AGLEE
931
ADQPP
936
LPGEQ
941
GINLD
946
NSGPK
951
LPEFS
956
NRPPG
961
YPSQP
966
VEQRP
971
LQQMP
976
PQLMQ
981
HVAPP
986
PQPPQ
991
QQPQP
996
QLPQQ
1001
QQPPP
1006
PSQPQ
1011
SQQQQ
1016
QQQQQ
1021
MMMML
1026
MMQQD
1031
PKSVR
1036
LPVSQ
1041
NVHPP
1046
RGPLN
1051
PDSQR
1056
MPMQQ
1061
SGSVP
1066
VMVSL
1071
QGPAS
1076
VPPSP
1081
DKQRM
1086
PMPVN
1091
TPLGS
1096
NSRKM
1101
VYQES
1106
PQNPS
1111
SSPLA
1116
EMASL
1121
PEASG
1126
SEAPS
1131
VPGGP
1136
NNMPS
1141
HVVLP
1146
QNQLM
1151
MTGPK
1156
PGPSP
1161
LSATQ
1166
GATPQ
1171
QPPVN
1176
SLPSS
1181
HGHHF
1186
PNVAA
1191
PTQTS
1196
RPKTP
1201
NRASP
1206
RPYYP
1211
QTPNN
1216
RPPST
1221
EPSEI
1226
SLSPE
1231
RLNAS
1236
IAGLF
1241
PPQIN
1246
IPLPP
1251
RPNLN
1256
RGFDQ
1261
QGLNP
1266
TTLKA
1271
IGQAP
1276
SNLTM
1281
NPSNF
1286
ATPQT
1291
HKLDS
1296
VVVNS
1301
GKQSN
1306
SGATK
1311
RASPS
1316
NSRRS
1321
SPGSS
1326
RKTTP
1331
SPGRQ
1336
NSKAP
1341
KLTLA
1346
SQTNA
1351
ALLQN
1356
VELPR
1361
NVLVS
1366
PTPLA
1371
NPPVP
1376
GSFPN
1381
NSGLN
1386
PQNST
1391
VSVAA
1396
VGGVV
1401
EDNKE
1406
SLNVP
1411
QDSDC
1416
QNSQS
1421
RKEQV
1426
NIELK
1431
AVPAQ
1436
EVKMV
1441
VPEDQ
1446
SKKDG
1451
QPSDP
1456
NKLPS
1461
VEENK
1466
NLVSP
1471
AMREA
1476
PTSLS
1481
QLLDN
1486
SGAPN
1491
VTIKP
1496
PGLTD
1501
LEVTP
1506
PVVSG
1511
EDLKK
1516
ASVIP
1521
TLQDL
1526
SSSKE
1531
PSNSL
1536
NLPHS
1541
NELCS
1546
SLVHP
1551
ELSEV
1556
SSNVA
1561
PSIPP
1566
VMSRP
1571
VSSSS
1576
ISTPL
1581
PPNQI
1586
TVFVT
1591
SNPIT
1596
TSANT
1601
SAALP
1606
THLQS
1611
ALMST
1616
VVTMP
1621
NAGSK
1626
VMVSE
1631
GQSAA
1636
QSNAR
1641
PQFIT
1646
PVFIN
1651
SSSII
1656
QVMKG
1661
SQPST
1666
IPAAP
1671
LTTNS
1676
GLMPP
1681
SVAVV
1686
GPLHI
1691
PQNIK
1696
FSSAP
1701
VPPNA
1706
LSSSP
1711
APNIQ
1716
TGRPL
1721
VLSSR
1726
ATPVQ
1731
LPSPP
1736
CTSSP
1741
VVPSH
1746
PPVQQ
1751
VKELN
1756
PDEAS
1761
PQVNT
1766
SADQN
1771
TLPSS
1776
QSTTM
1781
VSPLL
1786
TNSPG
1791
SSGNR
1796
RSPVS
1801
SSKGK
1806
GKVDK
1811
IGQIL
1816
LTKAC
1821
KKVTG
1826
SLEKG
1831
EEQYG
1836
ADGET
1841
EGQGL
1846
DTTAP
1851
GLMGT
1856
EQLST
1861
ELDSK
1866
TPTPP
1871
APTLL
1876
KMTSS
1881
PVGPG
1886
TASAG
1891
PSLPG
1896
GALPT
1901
SVRSI
1906
VTTLV
1911
PSELI
1916
SAVPT
1921
TKSNH
1926
GGIAS
1931
ESLAG
1936
GLVEE
1941
KVGSH
1946
PELLP
1951
SIAPS
1956
QNLVS
1961
KETST
1966
TALQA
1971
SVARP
1976
ELEVN
1981
AAIVS
1986
GQSSE
1991
PKEIV
1996
EKSKI
2001
PGRRN
2006
SRTEE
2011
PTVAS
2016
ESVEN
2021
GHRKR
2026
SSRPA
2031
SASSS
2036
TKDIT
2041
SAVQS
2046
KRRKS
2051
K
2056
Mutation Information
DNA mutation:
None
Peptide Range:
1360 ~ 1380
Mut AA position:
1371 (5 in Wild Type peptide)
Alignment
Wild Type:
"----NVELPRNVL--------
||||.||||
Mutant:
ALLQNVELRRNVLVSPTPLAN"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) NCOA6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay