Immunogenicity 430

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ADARB1
Transcript ID
None
HLA INFO
A*24:02
TCR INFO

No TCR info found!

T cell Tumor cell A*24:02
sequence
Full length protein sequence (741 aa)
MDIED
1
EENMS
6
SSSTD
11
VKENR
16
NLDNV
21
SPKDG
26
STPGP
31
GEGSQ
36
LSNGG
41
GGGPG
46
RKRPL
51
EEGSN
56
GHSKY
61
RLKKR
66
RKTPG
71
PVLPK
76
NALMQ
81
LNEIK
86
PGLQY
91
TLLSQ
96
TGPVH
101
APLFV
106
MSVEV
111
NGQVF
116
EGSGP
121
TKKKA
126
KLHAA
131
EKALR
136
SFVQF
141
PNASE
146
AHLAM
151
GRTLS
156
VNTDF
161
TSDQA
166
DFPDT
171
LFNGF
176
ETPDK
181
AEPPF
186
YVGSN
191
GDDSF
196
SSSGD
201
LSLSA
206
SPVPA
211
SLAQP
216
PLPVL
221
PPFPP
226
PSGKN
231
PVMIL
236
NELRP
241
GLKYD
246
FLSES
251
GESHA
256
KSFVM
261
SVVVD
266
GQFFE
271
GSGRN
276
KKLAK
281
ARAAQ
286
SALAA
291
IFNLH
296
LDQTP
301
SRQPI
306
PSEGL
311
QLHLP
316
QVLAD
321
AVSRL
326
VLGKF
331
GDLTD
336
NFSSP
341
HARRK
346
VLAGV
351
VMTTG
356
TDVKD
361
AKVIS
366
VSTGT
371
KCING
376
EYMSD
381
RGLAL
386
NDCHA
391
EIISR
396
RSLLR
401
FLYTQ
406
LELYL
411
NNKDD
416
QKRSI
421
FQKSE
426
RGGFR
431
LKENV
436
QFHLY
441
ISTSP
446
CGDAR
451
IFSPH
456
EPILE
461
GSRSY
466
TQAGV
471
QWCNH
476
GSLQP
481
RPPGL
486
LSDPS
491
TSTFQ
496
GAGTT
501
EPADR
506
HPNRK
511
ARGQL
516
RTKIE
521
SGEGT
526
IPVRS
531
NASIQ
536
TWDGV
541
LQGER
546
LLTMS
551
CSDKI
556
ARWNV
561
VGIQG
566
SLLSI
571
FVEPI
576
YFSSI
581
ILGSL
586
YHGDH
591
LSRAM
596
YQRIS
601
NIEDL
606
PPLYT
611
LNKPL
616
LSGIS
621
NAEAR
626
QPGKA
631
PNFSV
636
NWTVG
641
DSAIE
646
VINAT
651
TGKDE
656
LGRAS
661
RLCKH
666
ALYCR
671
WMRVH
676
GKVPS
681
HLLRS
686
KITKP
691
NVYHE
696
SKLAA
701
KEYQA
706
AKARL
711
FTAFI
716
KAGLG
721
AWVEK
726
PTEQD
731
QFSLT
736
P
741
Mutation Information
DNA mutation:
None
Peptide Range:
334 ~ 353
Mut AA position:
340 (7 in Wild Type peptide)
Alignment
Wild Type:
"-----KFGDLTDNF------
||||||.||
Mutant:
RLVLGKFGDLTNNFSSPHAR"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) ADARB1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay