Immunogenicity 431
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZBED4
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1171 aa)
MENNL
1
KTCPK
6
EDGDF
11
VSDKI
16
KFKIE
21
EEDDD
26
GIPPD
31
SLERM
36
DFKSE
41
QEDMK
46
QTDSG
51
GERAG
56
LGGTG
61
CSCKP
66
PGKYL
71
SAESE
76
DDYGA
81
LFSQY
86
SSTLY
91
DVAME
96
AVTQS
101
LLSSR
106
NMSSR
111
KKSPA
116
WKHFF
121
ISPRD
126
STKAI
131
CMYCV
136
KEFSR
141
GKNEK
146
DLSTS
151
CLMRH
156
VRRAH
161
PTVLI
166
QENGS
171
VSAVS
176
SFPSP
181
SLLLP
186
PQPAD
191
AGDLS
196
TILSP
201
IKLVQ
206
KVASK
211
IPSPD
216
RITEE
221
SVSVV
226
SSEEI
231
SSDMS
236
VSEKC
241
GREEA
246
LVGSS
251
PHLPA
256
LHYDE
261
PAENL
266
AEKSL
271
PLPKS
276
TSGSR
281
RRSAV
286
WKHFY
291
LSPLD
296
NSKAV
301
CIHCM
306
NEFSR
311
GKNGK
316
DLGTS
321
CLIRH
326
MWRAH
331
RAIVL
336
QENGG
341
TGIPP
346
LYSTP
351
PTLLP
356
SLLPP
361
EGELS
366
SVSSS
371
PVKPV
376
RESPS
381
ASSSP
386
DRLTE
391
DLQSH
396
LNPGD
401
GLMED
406
VAAFS
411
SSDDI
416
GEASA
421
SSPEK
426
QQADG
431
LSPRL
436
FESGA
441
IFQQN
446
KKVMK
451
RLKSE
456
VWHHF
461
SLAPM
466
DSLKA
471
ECRYC
476
GCAIS
481
RGKKG
486
DVGTS
491
CLMRH
496
LYRRH
501
PEVVG
506
SQKGF
511
LGASL
516
ANSPY
521
ATLAS
526
AESSS
531
SKLTD
536
LPTVV
541
TKNNQ
546
VMFPV
551
NSKKT
556
SKLWN
561
HFSIC
566
SADST
571
KVVCL
576
HCGRT
581
ISRGK
586
KPTNL
591
GTSCL
596
LRHLQ
601
RFHSN
606
VLKTE
611
VSETA
616
RPSSP
621
DTRVP
626
RGTEL
631
SGASS
636
FDDTN
641
EKFYD
646
SHPVA
651
KKITS
656
LIAEM
661
IALDL
666
QPYSF
671
VDNVG
676
FNRLL
681
EYLKP
686
QYSLP
691
APSYF
696
SRTAI
701
PGMYD
706
NVKQI
711
IMSHL
716
KEAES
721
GVIHF
726
TSGIW
731
MSNQT
736
REYLT
741
LTAHW
746
VSFES
751
PARPR
756
CDDHH
761
CSALL
766
DVSQV
771
DCDYS
776
GNSIQ
781
KQLEC
786
WWEAW
791
VTSTG
796
LQVGI
801
TVTDN
806
ASIGK
811
TLNEG
816
EHSSV
821
QCFSH
826
TVNLI
831
VSEAI
836
KSQRM
841
VQNLL
846
SLARK
851
ICERV
856
HRSPK
861
AKEKL
866
AELQR
871
EYALP
876
QHHLI
881
QDVPS
886
KWSTS
891
FHMLE
896
RLIEQ
901
KRAIN
906
EMSVE
911
CNFRE
916
LISCD
921
QWEVM
926
QSVCR
931
ALKPF
936
EAASR
941
EMSTQ
946
MSTLS
951
QVIPM
956
VHILN
961
RKVEM
966
LFEET
971
MGIDT
976
MLRSL
981
KEAMV
986
SRLSA
991
TLHDP
996
RYVFA
1001
TLLDP
1006
RYKAS
1011
LFTEE
1016
EAEQY
1021
KQDLI
1026
RELEL
1031
MNSTS
1036
EDVAA
1041
SHRCD
1046
AGSPS
1051
KDSAA
1056
EENLW
1061
SLVAK
1066
VKKKD
1071
PREKL
1076
PEAMV
1081
LAYLE
1086
EEVLE
1091
HSCDP
1096
LTYWN
1101
LKKAS
1106
WPGLS
1111
ALAVR
1116
FLGCP
1121
PSIVP
1126
SEKLF
1131
NTPTE
1136
NGSLG
1141
QSRLM
1146
MEHFE
1151
KLIFL
1156
KVNLP
1161
LIYFQ
1166
Y
1171
Mutation Information
DNA mutation:
None
Peptide Range:
209 ~ 232
Mut AA position:
218 (10 in Wild Type peptide)
Alignment
Wild Type:
"-----VQKVASKIPS---------
|||||||||.
Mutant:
SPIKLVQKVASKIPFPDRITEESV"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) ZBED4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay