Immunogenicity 4319

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
METTL24
Transcript ID
NM_001123364
HLA INFO
B*18:01
TCR INFO

No TCR info found!

T cell Tumor cell B*18:01
sequence
Full length protein sequence (366 aa)
MARER
1
PPGRG
6
CGVLR
11
RCLLG
16
AVLLF
21
GLRLC
26
AELRR
31
AGPGS
36
PTRSA
41
PPGPA
46
WRPPG
51
PHLPP
56
APGQP
61
RGASR
66
RQVTY
71
VRSGR
76
RAPPG
81
GGGSG
86
TPEPG
91
CCAPR
96
GRPRR
101
KGPRW
106
HIDLQ
111
PWAGS
116
AQSLD
121
EEAWR
126
FLRYI
131
STTQI
136
ACNHM
141
NTDSL
146
ATDSS
151
PTHKP
156
WSVCL
161
DDRFN
166
LAHQI
171
RNKQC
176
RLYSL
181
GLGSD
186
DTHFE
191
VSMAN
196
NGCEV
201
HRFDP
206
SVKSA
211
HILES
216
QHLWY
221
HRLSI
226
DWRDP
231
HPAVA
236
AQKPH
241
SNTRK
246
LGSIL
251
NEFGH
256
HKIDV
261
LKADL
266
ESAEW
271
KVLEN
276
LILED
281
VLEQI
286
GQLIF
291
EIHLH
296
WPGFE
301
VSGSD
306
SSVVR
311
FWYSL
316
LKELE
321
QKDFR
326
LFHSY
331
KDLSK
336
PQLFL
341
KKDIF
346
NASSC
351
YTLSW
356
VNTRW
361
K
366
Mutation Information
DNA mutation:
None
Peptide Range:
16 ~ 40
Mut AA position:
28 (13 in Wild Type peptide)
Alignment
Wild Type:
"RCLLGAVLLFGLRLCAELRRAGPGS
||||||||||||.||||||||||||
Mutant:
RCLLGAVLLFGLQLCAELRRAGPGS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) METTL24

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay