Immunogenicity 4348

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
OR2M3
Transcript ID
NM_001004689
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (312 aa)
MAREN
1
STFNS
6
DFILL
11
GIFNH
16
SPTHT
21
FLFFL
26
VLAIF
31
SVAFM
36
GNSVM
41
VLLIY
46
LDTQL
51
HTPMY
56
LLLSQ
61
LSLMD
66
LMLIC
71
TTVPK
76
MAFNY
81
LSGSK
86
SISMA
91
GCATQ
96
IFFYT
101
SLLGS
106
ECFLL
111
AVMAY
116
DRYTA
121
ICHPL
126
RYTNL
131
MSPKI
136
CGLMT
141
AFSWI
146
LGSTD
151
GIIDV
156
VATFS
161
FSYCG
166
SREIA
171
HFFCD
176
FPSLL
181
ILSCS
186
DTSIF
191
EKILF
196
ICCIV
201
MIVFP
206
VAIII
211
ASYAR
216
VILAV
221
IHMGS
226
GEGRR
231
KAFTT
236
CSSHL
241
LVVGM
246
YYGAA
251
LFMYI
256
RPTSD
261
RSPTQ
266
DKMVS
271
VFYTI
276
LTPML
281
NPLIY
286
SLRNK
291
EVTRA
296
FMKIL
301
GKGKS
306
GE
311
Mutation Information
DNA mutation:
None
Peptide Range:
102 ~ 126
Mut AA position:
114 (13 in Wild Type peptide)
Alignment
Wild Type:
"FFYTSLLGSECFLLAVMAYDRYTAI
||||||||||||.||||||||||||
Mutant:
FFYTSLLGSECFPLAVMAYDRYTAI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OR2M3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay