Immunogenicity 435
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MECOM
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1240 aa)
MRSKG
1
RARKL
6
ATNNE
11
CVYGN
16
YPEIP
21
LEEMP
26
DADGV
31
ASTPS
36
LNIQE
41
PCSPA
46
TSSEA
51
FTPKE
56
GSPYK
61
APIYI
66
PDDIP
71
IPAEF
76
ELRES
81
NMPGA
86
GLGIW
91
TKRKI
96
EVGEK
101
FGPYV
106
GEQRS
111
NLKDP
116
SYGWE
121
ILDEF
126
YNVKF
131
CIDAS
136
QPDVG
141
SWLKY
146
IRFAG
151
CYDQH
156
NLVAC
161
QINDQ
166
IFYRV
171
VADIA
176
PGEEL
181
LLFMK
186
SEDYP
191
HETMA
196
PDIHE
201
ERQYR
206
CEDCD
211
QLFES
216
KAELA
221
DHQKF
226
PCSTP
231
HSAFS
236
MVEED
241
FQQKL
246
ESEND
251
LQEIH
256
TIQEC
261
KECDQ
266
VFPDL
271
QSLEK
276
HMLSH
281
TEERE
286
YKCDQ
291
CPKAF
296
NWKSN
301
LIRHQ
306
MSHDS
311
GKHYE
316
CENCA
321
KQVFT
326
DPSNL
331
QRHIR
336
SQHVG
341
ARAHA
346
CPECG
351
KTFAT
356
SSGLK
361
QHKHI
366
HSSVK
371
PFICE
376
VCHKS
381
YTQFS
386
NLCRH
391
KRMHA
396
DCRTQ
401
IKCKD
406
CGQMF
411
STTSS
416
LNKHR
421
RFCEG
426
KNHFA
431
AGGFF
436
GQGIS
441
LPGTP
446
AMDKT
451
SMVNM
456
SHANP
461
GLADY
466
FGANR
471
HPAGL
476
TFPTA
481
PGFSF
486
SFPGL
491
FPSGL
496
YHRPP
501
LIPAS
506
SPVKG
511
LSSTE
516
QTNKS
521
QSPLM
526
THPQI
531
LPATQ
536
DILKA
541
LSKHP
546
SVGDN
551
KPVEL
556
QPERS
561
SEERP
566
FEKIS
571
DQSES
576
SDLDD
581
VSTPS
586
GSDLE
591
TTSGS
596
DLESD
601
IESDK
606
EKFKE
611
NGKMF
616
KDKVS
621
PLQNL
626
ASINN
631
KKEYS
636
NHSIF
641
SPSLE
646
EQTAV
651
SGAVN
656
DSIKA
661
IASIA
666
EKYFG
671
STGLV
676
GLQDK
681
KVGAL
686
PYPSM
691
FPLPF
696
FPAFS
701
QSMYP
706
FPDRD
711
LRSLP
716
LKMEP
721
QSPGE
726
VKKLQ
731
KGSSE
736
SPFDL
741
TTKRK
746
DEKPL
751
TPVPS
756
KPPVT
761
PATSQ
766
DQPLD
771
LSMGS
776
RSRAS
781
GTKLT
786
EPRKN
791
HVFGG
796
KKGSN
801
VESRP
806
ASDGS
811
LQHAR
816
PTPFF
821
MDPIY
826
RVEKR
831
KLTDP
836
LEALK
841
EKYLR
846
PSPGF
851
LFHPQ
856
FQLPD
861
QRTWM
866
SAIEN
871
MAEKL
876
ESFSA
881
LKPEA
886
SELLQ
891
SVPSM
896
FNFRA
901
PPNAL
906
PENLL
911
RKGKE
916
RYTCR
921
YCGKI
926
FPRSA
931
NLTRH
936
LRTHT
941
GEQPY
946
RCKYC
951
DRSFS
956
ISSNL
961
QRHVR
966
NIHNK
971
EKPFK
976
CHLCD
981
RCFGQ
986
QTNLD
991
RHLKK
996
HENGN
1001
MSGTA
1006
TSSPH
1011
SELES
1016
TGAIL
1021
DDKED
1026
AYFTE
1031
IRNFI
1036
GNSNH
1041
GSQSP
1046
RNVEE
1051
RMNGS
1056
HFKDE
1061
KALVT
1066
SQNSD
1071
LLDDE
1076
EVEDE
1081
VLLDE
1086
EDEDN
1091
DITGK
1096
TGKEP
1101
VTSNL
1106
HEGNP
1111
EDDYE
1116
ETSAL
1121
EMSCK
1126
TSPVR
1131
YKEEE
1136
YKSGL
1141
SALDH
1146
IRHFT
1151
DSLKM
1156
RKMED
1161
NQYSE
1166
AELSS
1171
FSTSH
1176
VPEEL
1181
KQPLH
1186
RKSKS
1191
QAYAM
1196
MLSLS
1201
DKESL
1206
HSTSH
1211
SSSNV
1216
WHSMA
1221
RAAAE
1226
SSAIQ
1231
SISHV
1236
Mutation Information
DNA mutation:
None
Peptide Range:
216 ~ 234
Mut AA position:
216 (1 in Wild Type peptide)
Alignment
Wild Type:
"----QLFESKAELA-----
.|||||||||
Mutant:
EDSDKLFESKAELADHQKF"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) MECOM
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay