Immunogenicity 4356

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ZNF391
Transcript ID
NM_001076781
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (358 aa)
MESLR
1
GNTAQ
6
GPTNE
11
EDYKN
16
EGQLS
21
RQTKC
26
PAQKK
31
SSFEN
36
TVVRK
41
VSVTL
46
KEIFT
51
GEEGP
56
ESSEF
61
SLSPN
66
LDAQQ
71
KIPKG
76
HGSPI
81
SRKNS
86
KDNSD
91
LIKHQ
96
RLFSQ
101
RKPCK
106
CNECE
111
KAFSY
116
QSDLL
121
VHSRI
126
HGGEK
131
PFECN
136
KCGKS
141
FSRST
146
HLIEH
151
QRTHT
156
GEKPY
161
ECNEC
166
GKAFS
171
RSTHL
176
SLHQR
181
IHTGE
186
KPYEC
191
SECGK
196
AFSRS
201
TNLSQ
206
HQRTH
211
TQERP
216
YKCNE
221
CGKAF
226
GDRST
231
IIQHQ
236
RIHTG
241
ENPYE
246
CSKCG
251
KAFSW
256
ISSLT
261
EHQRT
266
HTGEN
271
PYECS
276
ECGKV
281
FSRSS
286
SLTEH
291
QRIHS
296
GEKPH
301
ECRVC
306
GKGFS
311
RSSSL
316
IIHQR
321
THTGE
326
KPYKC
331
NDCGK
336
AFCQS
341
STLIR
346
HQHLH
351
TKE
356
Mutation Information
DNA mutation:
None
Peptide Range:
302 ~ 326
Mut AA position:
314 (13 in Wild Type peptide)
Alignment
Wild Type:
"EKPHECRVCGKGFSRSSSLIIHQRT
||||||||||||.||||||||||||
Mutant:
EKPHECRVCGKGLSRSSSLIIHQRT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF391

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay