Immunogenicity 437

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CCSER1
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (932 aa)
MGDSG
1
SRRST
6
LVSRL
11
PIFRR
16
SINRR
21
HDSLP
26
SSPSS
31
SNTVG
36
VHSSS
41
PSSTN
46
SSSGS
51
TGKRR
56
SIFRT
61
PSISF
66
HHKKG
71
SEPKQ
76
EPTNQ
81
NLSIS
86
NGAQP
91
GHSNM
96
QKLSL
101
EEHIK
106
TRGRH
111
SVGFS
116
SSRNK
121
KITRS
126
LTEDF
131
EREKE
136
HSTNK
141
NVFIN
146
CLSSG
151
KSEGD
156
DSGFT
161
EDQTR
166
RSVKQ
171
STRKL
176
LPKSF
181
SSHYK
186
FSKPV
191
LQSQS
196
ISLVQ
201
QSEFS
206
LEVTQ
211
YQERE
216
PVLVR
221
ASPSC
226
SVDVT
231
ERAGS
236
SLQSP
241
LLSAD
246
LTTAQ
251
TPSEF
256
LALTE
261
DSVSE
266
MDAFS
271
KSGSM
276
ASHCD
281
NFGHN
286
DSTSQ
291
MSLNS
296
AAVTK
301
TTTEL
306
TGTVP
311
CAIMS
316
PGKYR
321
LEGQC
326
STESN
331
SLPET
336
SAANQ
341
KEVLL
346
QIAEL
351
PATSV
356
SHSES
361
NLPAD
366
SEREE
371
NIGLQ
376
NGETM
381
LGTNS
386
PRKLG
391
FYEQH
396
KAIAE
401
HVKGI
406
HPISD
411
SKIIP
416
TSGDH
421
HIFNK
426
TSHGY
431
EANPA
436
KVLAS
441
SLSPF
446
REGRF
451
IERRL
456
RSSSE
461
GTAGS
466
SRMIL
471
KPKDG
476
NIEEV
481
NSLRK
486
QRAGS
491
SSSKM
496
NSLDV
501
LNNLG
506
SCELD
511
EDDLM
516
LDLEF
521
LEEQS
526
LHPSE
531
LPQEH
536
TRKAK
541
RIHRP
546
LKELD
551
HRHRL
556
PEMAK
561
NFCRE
566
DSYHS
571
VVSCA
576
AVVLT
581
PMEPM
586
IEMKK
591
REEPE
596
FPEPS
601
KQNLS
606
LKLTK
611
DVDQE
616
ARCSH
621
ISRMP
626
NSPSA
631
DWPLQ
636
GVEEN
641
GGIDS
646
LPFRL
651
MLQDC
656
TAVKT
661
LLLKM
666
KRVLQ
671
ESADM
676
SPASS
681
TTSLP
686
VSPLT
691
EEPVP
696
FKDIM
701
KDECS
706
MLKLQ
711
LKEKD
716
ELISQ
721
LQEEL
726
GKVRH
731
LQKAF
736
ASRVD
741
KSTQT
746
ELLCY
751
DGLNL
756
KRLET
761
VQGGR
766
EATYR
771
NRIVS
776
QNLST
781
RDRKA
786
IHTPT
791
EDRFR
796
YSAAD
801
QTSPY
806
KNKTC
811
QLPSL
816
CLSNF
821
LKDKE
826
LAEVI
831
KHSRG
836
TYETL
841
TSDVT
846
QNLRA
851
TVGQS
856
SLKPT
861
AKTEG
866
LSTFL
871
EKPKD
876
QVATA
881
RQHST
886
FTGRF
891
GQPPR
896
GPISL
901
HMYSR
906
KNVFL
911
HHNLH
916
STELQ
921
TLGQQ
926
DG
931
Mutation Information
DNA mutation:
None
Peptide Range:
195 ~ 216
Mut AA position:
195 (1 in Wild Type peptide)
Alignment
Wild Type:
"---------VLQSQSISLV---
.|||||||||
Mutant:
SSHYKFSKPALQSQSISLVQQS"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) FAM190A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay