Immunogenicity 438

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TBC1D14
Transcript ID
None
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (727 aa)
MTDGK
1
LSTST
6
NGVAF
11
MGILD
16
GRPGN
21
PLQNL
26
QHVNL
31
KAPRL
36
LSAPE
41
YGPKL
46
KLRAL
51
EDRHS
56
LQSVD
61
SGIPT
66
LEIGN
71
PEPVP
76
CSAVH
81
VRRKQ
86
SDSDL
91
IPERA
96
FQSAC
101
ALPSC
106
APPAP
111
SSTER
116
EQSVR
121
KSSTF
126
PRTGY
131
DSVKL
136
YSPTS
141
KALTR
146
SDDVS
151
VCSVS
156
SLGTE
161
LSTTL
166
SVSNE
171
DILDL
176
VVTSS
181
SSAIV
186
TLEND
191
DDPQF
196
TNVTL
201
SSIKE
206
TRGLH
211
QQDCV
216
HEAEE
221
GSKLK
226
ILGPF
231
SNFFA
236
RNLLA
241
RKQSA
246
RLDKH
251
NDLGW
256
KLFGK
261
APLRE
266
NAQKD
271
SKRIQ
276
KEYED
281
KAGRP
286
SKPPS
291
PKQNV
296
RKNLD
301
FEPLS
306
TTALI
311
LEDRP
316
ANLPA
321
KPAEE
326
AQKHR
331
QQYEE
336
MVVQA
341
KKREL
346
KEAQR
351
RKKQL
356
EERCR
361
VEESI
366
GNAVL
371
TWNNE
376
ILPNW
381
ETMWC
386
SRKVR
391
DLWWQ
396
GIPPS
401
VRGKV
406
WSLAI
411
GNELN
416
ITHEL
421
FDICL
426
ARAKE
431
RWRSL
436
STGGS
441
EVENE
446
DAGFS
451
AADRE
456
ASLEL
461
IKLDI
466
SRTFP
471
NLCIF
476
QQVLI
481
FVDFR
486
VGLQK
491
SFQKR
496
KERES
501
TKLQQ
506
LWSWC
511
LGGPY
516
HDMLH
521
SILGA
526
YTCYR
531
PDVGY
536
VQGMS
541
FIAAV
546
LILNL
551
DTADA
556
FIAFS
561
NLLNK
566
PCQMA
571
FFRVD
576
HGLML
581
TYFAA
586
FEVFF
591
EENLP
596
KLFAH
601
FKKNN
606
LTPDI
611
YLIDW
616
IFTLY
621
SKSLP
626
LDLAC
631
RIWDV
636
FCRDG
641
EEFLF
646
RTALG
651
ILKLF
656
EDILT
661
KMDFI
666
HMAQF
671
LTRLP
676
EDLPA
681
EELFA
686
SIATI
691
QMQSR
696
NKKWA
701
QVLTA
706
LQKDS
711
REMEK
716
GSPSL
721
RH
726
Mutation Information
DNA mutation:
None
Peptide Range:
40 ~ 66
Mut AA position:
42 (3 in Wild Type peptide)
Alignment
Wild Type:
"------LLSAPEYGPK-----------
||.|||||||
Mutant:
NLKAPRLLFAPEYGPKLKLRALEDRHS"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) TBC1D14

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay