Immunogenicity 4382

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
OR4K14
Transcript ID
NM_001004712
HLA INFO
A*29:02
TCR INFO

No TCR info found!

T cell Tumor cell A*29:02
sequence
Full length protein sequence (310 aa)
MDPQN
1
YSLVS
6
EFVLH
11
GLCTS
16
RHLQN
21
FFFIF
26
FFGVY
31
VAIML
36
GNLLI
41
LVTVI
46
SDPCL
51
HSSPM
56
YFLLG
61
NLAFL
66
DMWLA
71
SFATP
76
KMIRD
81
FLSDQ
86
KLISF
91
GGCMA
96
QIFFL
101
HFTGG
106
AEMVL
111
LVSMA
116
YDRYV
121
AICKP
126
LHYMT
131
LMSWQ
136
TCIRL
141
VLASW
146
VVGFV
151
HSISQ
156
VAFTV
161
NLPYC
166
GPNEV
171
DSFFC
176
DLPLV
181
IKLAC
186
MDTYV
191
LGIIM
196
ISDSG
201
LLSLS
206
CFLLL
211
LISYT
216
VILLA
221
IRQRA
226
AGSTS
231
KALST
236
CSAHI
241
MVVTL
246
FFGPC
251
IFVYV
256
RPFSR
261
FSVDK
266
LLSVF
271
YTIFT
276
PLLNP
281
IIYTL
286
RNEEM
291
KAAMK
296
KLQNR
301
RVTFQ
306
Mutation Information
DNA mutation:
None
Peptide Range:
229 ~ 253
Mut AA position:
241 (13 in Wild Type peptide)
Alignment
Wild Type:
"RAAGSTSKALSTCSAHIMVVTLFFG
||||||||||||.||||||||||||
Mutant:
RAAGSTSKALSTFSAHIMVVTLFFG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OR4K14

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay