Immunogenicity 4391

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
OR4N4
Transcript ID
NM_001005241
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
sequence
Full length protein sequence (316 aa)
MKIAN
1
NTVVT
6
EFILL
11
GLTQS
16
QDIQL
21
LVFVL
26
ILIFY
31
LIILP
36
GNFLI
41
IFTIR
46
SDPGL
51
TAPLY
56
LFLGN
61
LAFLD
66
ASYSF
71
IVAPR
76
MLVDF
81
LSEKK
86
VISYR
91
GCITQ
96
LFFLH
101
FLGGG
106
EGLLL
111
VVMAF
116
DRYIA
121
ICRPL
126
HCSTV
131
MNPRA
136
CYAMM
141
LALWL
146
GGFVH
151
SIIQV
156
VLILR
161
LPFCG
166
PNQLD
171
NFFCD
176
VRQVI
181
KLACT
186
DMFVV
191
ELLMV
196
FNSGL
201
MTLLC
206
FLGLL
211
ASYAV
216
ILCHV
221
RRAAS
226
EGKNK
231
AMSTC
236
TTRVI
241
IILLM
246
FGPAI
251
FIYMC
256
PFRAL
261
PADKM
266
VSLFH
271
TVIFP
276
LMNPM
281
IYTLR
286
NQEVK
291
TSMKR
296
LLSRH
301
VVCQV
306
DFIIR
311
N
316
Mutation Information
DNA mutation:
None
Peptide Range:
299 ~ 316
Mut AA position:
311 (13 in Wild Type peptide)
Alignment
Wild Type:
"KRLLSRHVVCQVDFIIRN
||||||||||||.|||||
Mutant:
KRLLSRHVVCQVHFIIRN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OR4N4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay