Immunogenicity 4409

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
OR8K5
Transcript ID
NM_001004058
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (307 aa)
MGQHN
1
LTVLT
6
EFILM
11
ELTRR
16
PELQI
21
PLFGV
26
FLVIY
31
LITVV
36
GNLTM
41
IILTK
46
LDSHL
51
HTPMY
56
FSIRH
61
LAFVD
66
LGNST
71
VICPK
76
VLANF
81
VVDRN
86
TISYY
91
ACAAQ
96
LAFFL
101
MFIIS
106
EFFIL
111
SAMAY
116
DRYVA
121
ICNPL
126
LYYVI
131
MSQRL
136
CHVLV
141
GIQYL
146
YSTFQ
151
ALMFT
156
IKIFT
161
LTFCG
166
SNVIS
171
HFYCD
176
DVPLL
181
PMLCS
186
NAQEI
191
ELLSI
196
LFSVF
201
NLISS
206
FLIVL
211
VSYML
216
ILLAI
221
CQMHS
226
AEGRK
231
KAFST
236
CGSHL
241
TVVVV
246
FYGSL
251
LFMYM
256
QPNST
261
HFFDT
266
DKMAS
271
VFYTL
276
VIPML
281
NPLIY
286
SLRNE
291
EVKNA
296
FYKLF
301
EN
306
Mutation Information
DNA mutation:
None
Peptide Range:
96 ~ 120
Mut AA position:
108 (13 in Wild Type peptide)
Alignment
Wild Type:
"ACAAQLAFFLMFIISEFFILSAMAY
||||||||||||.||||||||||||
Mutant:
ACAAQLAFFLMFFISEFFILSAMAY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OR8K5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay