Immunogenicity 4425

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PCDHB11
Transcript ID
NM_018931
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (797 aa)
MENQG
1
TRTQQ
6
IRQVL
11
LLFVL
16
LGMSQ
21
AGSET
26
WSFSV
31
AEEMQ
36
SGSFV
41
GNLAK
46
DLGLK
51
VRELS
56
SRGAR
61
VVSND
66
KKQRL
71
QLDIN
76
TGDLL
81
LSETL
86
DREEL
91
CGSIE
96
PCVLH
101
LQVLM
106
QNPTQ
111
FLQIE
116
LQVRD
121
INDHS
126
PIFSE
131
KQMLL
136
EIPEN
141
SPVGA
146
VFLLE
151
SAKDL
156
DVGIN
161
AVKSY
166
TISPN
171
SHFHI
176
KMRVI
181
PDNRK
186
YPELV
191
LDKAL
196
DYEEL
201
PELSF
206
ILSAL
211
DGGSP
216
PRSGT
221
ALVRV
226
VVVDI
231
NDNSP
236
EFEQA
241
FYEVK
246
IRENS
251
ILGSL
256
ILIVS
261
AWDLD
266
SGTNG
271
EICYT
276
FSHAS
281
EDIRK
286
TFEIN
291
QKSGE
296
ITLRA
301
PLDFE
306
TIESY
311
SIIIQ
316
ATDGG
321
GLFGK
326
STVII
331
HVIDV
336
NDNAP
341
EITVS
346
SITSP
351
IPENT
356
PETVV
361
MVFSI
366
QDIDS
371
GDNGR
376
IVCSI
381
PEDLP
386
FVLKS
391
SVENY
396
YTLET
401
ERPLD
406
RESTA
411
EYNIT
416
ITVTD
421
LGIPR
426
LKTEH
431
NTTVL
436
VSDVN
441
DNAPT
446
FTQTS
451
YTLFV
456
RENNS
461
PALHI
466
GSVSA
471
TDRDS
476
GTNAQ
481
VNYSL
486
LPPQD
491
LHLPL
496
ASLVS
501
INTDN
506
GHLFA
511
LRSLD
516
YEALQ
521
AFDFR
526
VGATD
531
RGSPA
536
LSSEA
541
LVRVL
546
VLDAN
551
DNSPF
556
VLYPL
561
QNGSA
566
PCTEL
571
VPRAA
576
EPGYL
581
VTKVV
586
AVDGD
591
SGQNA
596
WLSYQ
601
LLKAT
606
EPGLF
611
GVWAH
616
NGEVR
621
TARLL
626
SERDA
631
AKHRL
636
VVLVK
641
DNGEP
646
PRSAT
651
ATLQV
656
LLVDG
661
FSQPY
666
LPLPE
671
AAPAQ
676
AQADS
681
LTVYL
686
VVALA
691
SVSSL
696
FLFSV
701
LLFVA
706
VRLCR
711
RSRAA
716
SVGSC
721
SVPKG
726
PFPGH
731
LVDVS
736
GTGTL
741
SQSYQ
746
YEVCL
751
TGGSE
756
TNEFK
761
FLKPV
766
IPNIQ
771
AKGLG
776
KNSEE
781
NSTFR
786
NSFGF
791
NF
796
Mutation Information
DNA mutation:
None
Peptide Range:
513 ~ 537
Mut AA position:
525 (13 in Wild Type peptide)
Alignment
Wild Type:
"LFALRSLDYEALQAFDFRVGATDRG
||||||||||||.||||||||||||
Mutant:
LFALRSLDYEALRAFDFRVGATDRG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PCDHB11

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay