Immunogenicity 443
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PRRC2A
Transcript ID
None
HLA INFO
B*56:01
TCR INFO
No TCR info found!
Full length protein sequence (2086 aa)
MSDRS
1
GPTAK
6
GKDGK
11
KYSSL
16
NLFDT
21
YKGKS
26
LEIQK
31
PAVAP
36
RHGLQ
41
SLGKV
46
AIARR
51
MPPPA
56
NLPSL
61
KAENK
66
GNDPN
71
VSLVP
76
KDGTG
81
WASKQ
86
EQSDP
91
KSSDA
96
STAQP
101
PESQP
106
LPASQ
111
TPASN
116
QPKRP
121
PAAPE
126
NTPLV
131
PSGVK
136
SWAQA
141
SVTHG
146
AHGDG
151
GRASS
156
LLSRF
161
SREEF
166
PTLQA
171
AGDQD
176
KAAKE
181
RESAE
186
QSSGP
191
GPSLR
196
PQNST
201
TWRDG
206
GGRGP
211
DELEG
216
PDSKL
221
HHGHD
226
PRGGL
231
QPSGP
236
PQFPP
241
YRGMM
246
PPFMY
251
PPYLP
256
FPPPY
261
GPQGP
266
YRYPT
271
PDGPS
276
RFPRV
281
AGPRG
286
SGPPM
291
RLVEP
296
VGRPS
301
ILKED
306
NLKEF
311
DQLDQ
316
ENDDG
321
WAGAH
326
EEVDY
331
TEKLK
336
FSDEE
341
DGRDS
346
DEEGA
351
EGHRD
356
SQSAS
361
GEERP
366
PEADG
371
KKGNS
376
PNSEP
381
PTPKT
386
AWAET
391
SRPPE
396
TEPGP
401
PAPKP
406
PLPPP
411
HRGPA
416
GNWGP
421
PGDYP
426
DRGGP
431
PCKPP
436
APEDE
441
DEAWR
446
QRRKQ
451
SSSEI
456
SLAVE
461
RARRR
466
REEEE
471
RRMQE
476
ERRAA
481
CAEKL
486
KRLDE
491
KFGAP
496
DKRLK
501
AEPAA
506
PPAAP
511
STPAP
516
PPAVP
521
KELPA
526
PPAPP
531
PASAP
536
TPETE
541
PEEPA
546
QAPPA
551
QSTPT
556
PGVAA
561
APTLV
566
SGGGS
571
TSSTS
576
SGSFE
581
ASPVE
586
PQLPS
591
KEGPE
596
PPEEV
601
PPPTT
606
PPVPK
611
VEPKG
616
DGIGP
621
TRQPP
626
SQGLG
631
YPKYQ
636
KSLPP
641
RFQRQ
646
QQEQL
651
LKQQQ
656
QHQWQ
661
QHQQG
666
SAPPT
671
PVPPS
676
PPQPV
681
TLGAV
686
PAPQA
691
PPPPP
696
KALYP
701
GALGR
706
PPPMP
711
PMNFD
716
PRWMM
721
IPPYV
726
DPRLL
731
QGRPP
736
LDFYP
741
PGVHP
746
SGLVP
751
RERSD
756
SGGSS
761
SEPFD
766
RHAPA
771
MLRER
776
GTPPV
781
DPKLA
786
WVGDV
791
FTATP
796
AEPRP
801
LTSPL
806
RQAAD
811
EDDKG
816
MRSET
821
PPVPP
826
PPPYL
831
ASYPG
836
FPENG
841
APGPP
846
ISRFP
851
LEEPG
856
PRPLP
861
WPPGS
866
DEVAK
871
IQTPP
876
PKKEP
881
PKEET
886
AQLTG
891
PEAGR
896
KPARG
901
VGSGG
906
QGPPP
911
PRRES
916
RTETR
921
WGPRP
926
GSSRR
931
GIPPE
936
EPGAP
941
PRRAG
946
PIKKP
951
PPPTK
956
VEELP
961
PKPLE
966
QGDET
971
PKPPK
976
PDPLK
981
ITKGK
986
LGGPK
991
ETPPN
996
GNLSP
1001
APRLR
1006
RDYSY
1011
ERVGP
1016
TSCRG
1021
RGRGE
1026
YFARG
1031
RGFRG
1036
TYGGR
1041
GRGAR
1046
SREFR
1051
SYREF
1056
RGDDG
1061
RGGGT
1066
GGPNH
1071
PPAPR
1076
GRTAS
1081
ETRSE
1086
GSEYE
1091
EIPKR
1096
RRQRG
1101
SETGS
1106
ETHES
1111
DLAPS
1116
DKEAP
1121
TPKEG
1126
TLTQV
1131
PLAPP
1136
PPGAP
1141
PSPAP
1146
ARFTA
1151
RGGRV
1156
FTPRG
1161
VPSRR
1166
GRGGG
1171
RPPPQ
1176
VCPGW
1181
SPPAK
1186
SLAPK
1191
KPPTG
1196
PLPPS
1201
KEPLK
1206
EKLIP
1211
GPLSP
1216
VARGG
1221
SNGGS
1226
NVGME
1231
DGERP
1236
RRRRH
1241
GRAQQ
1246
QDKPP
1251
RFRRL
1256
KQERE
1261
NAARG
1266
SEGKP
1271
SLTLP
1276
ASAPG
1281
PEEAL
1286
TTVTV
1291
APAPR
1296
RAAAK
1301
SPDLS
1306
NQNSD
1311
QANEE
1316
WETAS
1321
ESSDF
1326
TSERR
1331
GDKEA
1336
PPPVL
1341
LTPKA
1346
VGTPG
1351
GGGGG
1356
AVPGI
1361
SAMSR
1366
GDLSQ
1371
RAKDL
1376
SKRSF
1381
SSQRP
1386
GMERQ
1391
NRRPG
1396
PGGKA
1401
GSSGS
1406
SSGGG
1411
GGGPG
1416
GRTGP
1421
GRGDK
1426
RSWPS
1431
PKNRS
1436
RPPEE
1441
RPPGL
1446
PLPPP
1451
PPSSS
1456
AVFRL
1461
DQVIH
1466
SNPAG
1471
IQQAL
1476
AQLSS
1481
RQGSV
1486
TAPGG
1491
HPRHK
1496
PGLPQ
1501
APQGP
1506
SPRPP
1511
TRYEP
1516
QRVNS
1521
GLSSD
1526
PHFEE
1531
PGPMV
1536
RGVGG
1541
TPRDS
1546
AGVSP
1551
FPPKR
1556
RERPP
1561
RKPEL
1566
LQEES
1571
LPPPH
1576
SSGFL
1581
GSKPE
1586
GPGPQ
1591
AESRD
1596
TGTEA
1601
LTPHI
1606
WNRLH
1611
TATSR
1616
KSYRP
1621
SSMEP
1626
WMEPL
1631
SPFED
1636
VAGTE
1641
MSQSD
1646
SGVDL
1651
SGDSQ
1656
VSSGP
1661
CSQRS
1666
SPDGG
1671
LKGAA
1676
EGPPK
1681
RPGGS
1686
SPLNA
1691
VPCEG
1696
PPGSE
1701
PPRRP
1706
PPAPH
1711
DGDRK
1716
ELPRE
1721
QPLPP
1726
GPIGT
1731
ERSQR
1736
TDRGT
1741
EPGPI
1746
RPSHR
1751
PGPPV
1756
QFGTS
1761
DKDSD
1766
LRLVV
1771
GDSLK
1776
AEKEL
1781
TASVT
1786
EAIPV
1791
SRDWE
1796
LLPSA
1801
AASAE
1806
PQSKN
1811
LDSGH
1816
CVPEP
1821
SSSGQ
1826
RLYPE
1831
VFYGS
1836
AGPSS
1841
SQISG
1846
GAMDS
1851
QLHPN
1856
SGGFR
1861
PGTPS
1866
LHPYR
1871
SQPLY
1876
LPPGP
1881
APPSA
1886
LLSGL
1891
ALKGQ
1896
FLDFS
1901
TMQAT
1906
ELGKL
1911
PAGGV
1916
LYPPP
1921
SFLYS
1926
PAFCP
1931
SPLPD
1936
TSLLQ
1941
VRQDL
1946
PSPSD
1951
FYSTP
1956
LQPGG
1961
QSGFL
1966
PSGAP
1971
AQQLH
1976
PVELK
1981
PFQDY
1986
QKLSS
1991
NLGGP
1996
GSSRT
2001
PPTGR
2006
SFSGL
2011
NSRLK
2016
ATPST
2021
YSGVF
2026
RTQRV
2031
DLYQQ
2036
ASPPD
2041
ALRWI
2046
PKPWE
2051
RTGPP
2056
PREGP
2061
SRRAE
2066
EPGSR
2071
GDKEP
2076
GLPPP
2081
R
2086
Mutation Information
DNA mutation:
None
Peptide Range:
524 ~ 548
Mut AA position:
528 (5 in Wild Type peptide)
Alignment
Wild Type:
"------VPKELPAPPA---------
||||.|||||
Mutant:
PAPPPAVPKEHPAPPAPPPASAPTP"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) PRRC2A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay