Immunogenicity 444

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZMIZ2
Transcript ID
None
HLA INFO
B*35:01
TCR INFO

No TCR info found!

T cell Tumor cell B*35:01
sequence
Full length protein sequence (929 aa)
MNSMN
1
PMKPA
6
LPPAP
11
HGDGS
16
FAYES
21
VPWQQ
26
SATQP
31
AGSLS
36
VVTTV
41
WGVGN
46
ATQSQ
51
VLGNP
56
MGPAG
61
SPSGS
66
SMMPG
71
VAGGS
76
SALTS
81
PQCLG
86
QQAFA
91
EGGAN
96
KGYVQ
101
QGVYS
106
RGGYP
111
GAPGF
116
TTGYA
121
GGPGG
126
LGLPS
131
HAARP
136
STDFT
141
QAAAA
146
AAVAA
151
AAATA
156
TATAT
161
ATVAA
166
LQEKQ
171
SQELS
176
QYGAM
181
GAGQS
186
FNSQF
191
LQHGG
196
PRGPS
201
VPAGM
206
NPTGI
211
GGVMG
216
PSGLS
221
PLAMN
226
PTRAA
231
GMTPL
236
YAGQR
241
LPQHG
246
YPGPP
251
QAQPL
256
PRQGV
261
KRTYS
266
EVYPG
271
QQYLQ
276
GGQYA
281
PSTAQ
286
FAPSP
291
GQPPA
296
PSPSY
301
PGHRL
306
PLQQG
311
MTQSL
316
SVPGP
321
TGLHY
326
KPTEQ
331
FNGQG
336
ASFNG
341
GSVSY
346
SQPGL
351
SGPTR
356
SIPGY
361
PSSPL
366
PGNPT
371
PPMTP
376
SSSVP
381
YMSPN
386
QEVKS
391
PFLPD
396
LKPNL
401
NSLHS
406
SPSAH
411
SQWPL
416
LPGSG
421
PCDEL
426
RLTFP
431
VRDGV
436
VLEPF
441
RLQHN
446
LAVSN
451
HVFQL
456
RDSVY
461
KTLIM
466
RPDLE
471
LQFKC
476
YHHED
481
RQMNT
486
NWPAS
491
VQVSV
496
NATPL
501
TIERG
506
DNKTS
511
HKPLY
516
LKHVC
521
QPGRN
526
TIQIT
531
VTACC
536
CSHLF
541
VLQLV
546
HRPSV
551
RSVLQ
556
GLLKK
561
RLLPA
566
EHCIT
571
KIKRN
576
FSSGT
581
IPGTP
586
GPNGE
591
DGVEQ
596
TAIKV
601
SLKCP
606
ITFRR
611
IQLPA
616
RGHDC
621
RHIQC
626
FDLES
631
YLQLN
636
CERGT
641
WRCPV
646
CNKTA
651
LLEGL
656
EVDQY
661
MLGIL
666
IYIQN
671
SDYEE
676
ITIDP
681
TCSWK
686
PVPVK
691
PDMHI
696
KEEPD
701
GPALK
706
RCRTV
711
SPAHV
716
LMPSV
721
MEMIA
726
ALGPG
731
AAPFA
736
PLQPP
741
SVPAP
746
SDYPG
751
QGSSF
756
LGPGT
761
FPESF
766
PPTTP
771
STPTL
776
AEFTP
781
GPPPI
786
SYQSD
791
IPSSL
796
LTSEK
801
STACL
806
PSQMA
811
PAGHL
816
DPTHN
821
PGTPG
826
LHTSN
831
LGAPP
836
GPQLH
841
HSNPP
846
PASRQ
851
SLGQA
856
SLGPT
861
GELAF
866
SPATG
871
VMGPP
876
SMSGA
881
GEAPE
886
PALDL
891
LPELT
896
NPDEL
901
LSYLG
906
PPDLP
911
TNNND
916
DLLSL
921
FENN
926
Mutation Information
DNA mutation:
None
Peptide Range:
292 ~ 319
Mut AA position:
301 (10 in Wild Type peptide)
Alignment
Wild Type:
"----APSPGQPPAP--------------
|||||||||.
Mutant:
TAQFAPSPGQPPALSPSYPGHRLPLQQG"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) ZMIZ2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay