Immunogenicity 4446

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCDHB10
Transcript ID
NM_018930
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (800 aa)
MAVRE
1
LCFPR
6
QRQVL
11
FLFLF
16
WGVSL
21
AGSGF
26
GRYSV
31
TEETE
36
KGSFV
41
VNLAK
46
DLGLA
51
EGELA
56
ARGTR
61
VVSDD
66
NKQYL
71
LLDSH
76
TGNLL
81
TNEKL
86
DREKL
91
CGPKE
96
PCMLY
101
FQILM
106
DDPFQ
111
IYRAE
116
LRVRD
121
INDHA
126
PVFQD
131
KETVL
136
KISEN
141
TAEGT
146
AFRLE
151
RAQDP
156
DGGLN
161
GIQNY
166
TISPN
171
SFFHI
176
NISGG
181
DEGMI
186
YPELV
191
LDKAL
196
DREEQ
201
GELSL
206
TLTAL
211
DGGSP
216
SRSGT
221
STVRI
226
VVLDV
231
NDNAP
236
QFAQA
241
LYETQ
246
APENS
251
PIGFL
256
IVKVW
261
AEDVD
266
SGVNA
271
EVSYS
276
FFDAS
281
ENIRT
286
TFQIN
291
PFSGE
296
IFLRE
301
LLDYE
306
LVNSY
311
KINIQ
316
AMDGG
321
GLSAR
326
CRVLV
331
EVLDT
336
NDNPP
341
ELIVS
346
SFSNS
351
VAENS
356
PETPL
361
AVFKI
366
NDRDS
371
GENGK
376
MVCYI
381
QENLP
386
FLLKP
391
SVENF
396
YILIT
401
EGALD
406
REIRA
411
EYNIT
416
ITVTD
421
LGTPR
426
LKTEH
431
NITVL
436
VSDVN
441
DNAPA
446
FTQTS
451
YTLFV
456
RENNS
461
PALHI
466
GSVSA
471
TDRDS
476
GTNAQ
481
VTYSL
486
LPPQD
491
PHLPL
496
ASLVS
501
INADN
506
GHLFA
511
LRSLD
516
YEALQ
521
AFEFR
526
VGATD
531
RGSPA
536
LSREA
541
LVRVL
546
VLDAN
551
DNSPF
556
VLYPL
561
QNGSA
566
PCTEL
571
VPRAA
576
EPGYL
581
VTKVV
586
AVDGD
591
SGQNA
596
WLSYQ
601
LLKAT
606
EPGLF
611
GVWAH
616
NGEVR
621
TARLL
626
SERDA
631
AKHRL
636
VVLVK
641
DNGEP
646
PRSAT
651
ATLHL
656
LLVDG
661
FSQPY
666
LPLPE
671
AAPAQ
676
AQAEA
681
DLLTV
686
YLVVA
691
LASVS
696
SLFLL
701
SVLLF
706
VAVRL
711
CRRSR
716
AASVG
721
RCSVP
726
EGPFP
731
GHLVD
736
VRGAE
741
TLSQS
746
YQYEV
751
CLTGG
756
PGTSE
761
FKFLK
766
PVISD
771
IQAQG
776
PGRKG
781
EENST
786
FRNSF
791
GFNIQ
796
Mutation Information
DNA mutation:
None
Peptide Range:
496 ~ 520
Mut AA position:
508 (13 in Wild Type peptide)
Alignment
Wild Type:
"PHLPLASLVSINADNGHLFALRSLD
||||||||||||.||||||||||||
Mutant:
PHLPLASLVSINTDNGHLFALRSLD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PCDHB10

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay