Immunogenicity 445
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CDK13
Transcript ID
None
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1542 aa)
MPSSS
1
DTALG
6
GGGGL
11
SWAEK
16
KLEER
21
RKRRR
26
FLSPQ
31
QPPLL
36
LPLLQ
41
PQLLQ
46
PPPPP
51
PPLLF
56
LAAPG
61
TAAAA
66
AAAAA
71
ASSSC
76
FSPGP
81
PLEVK
86
RLARG
91
KRRAG
96
GRQKR
101
RRGPR
106
AGQEA
111
EKRRV
116
FSLPQ
121
PQQDG
126
GGGAS
131
SGGGV
136
TPLVE
141
YEDVS
146
SQSEQ
151
GLLLG
156
GASAA
161
TAATA
166
AGGTG
171
GSGGS
176
PASSS
181
GTQRR
186
GEGSE
191
RRPRR
196
DRRSS
201
SGRSK
206
ERHRE
211
HRRRD
216
GQRGG
221
SEASK
226
SRSRH
231
SHSGE
236
ERAEV
241
AKSGS
246
SSSSG
251
GRRKS
256
ASATS
261
SSSSS
266
RKDRD
271
SKAHR
276
SRTKS
281
SKEPP
286
SAYKE
291
PPKAY
296
REDKT
301
EPKAY
306
RRRRS
311
LSPLG
316
GRDDS
321
PVSHR
326
ASQSL
331
RSRKS
336
PSPAG
341
GGSSP
346
YSRRL
351
PRSPS
356
PYSRR
361
RSPSY
366
SRHSS
371
YERGG
376
DVSPS
381
PYSSS
386
SWRRS
391
RSPYS
396
PVLRR
401
SGKSR
406
SRSPY
411
SSRHS
416
RSRSR
421
HRLSR
426
SRSRH
431
SSISP
436
STLTL
441
KSSLA
446
AELNK
451
NKKAR
456
AAEAA
461
RAAEA
466
AKAAE
471
ATKAA
476
EAAAK
481
AAKAS
486
NTSTP
491
TKGNT
496
ETSAS
501
ASQTN
506
HVKDV
511
KKIKI
516
EHAPS
521
PSSGG
526
TLKND
531
KAKTK
536
PPLQV
541
TKVEN
546
NLIVD
551
KATKK
556
AVIVG
561
KESKS
566
AATKE
571
ESVSL
576
KEKTK
581
PLTPS
586
IGAKE
591
KEQHV
596
ALVTS
601
TLPPL
606
PLPPM
611
LPEDK
616
EADSL
621
RGNIS
626
VKAVK
631
KEVEK
636
KLRCL
641
LADLP
646
LPPEL
651
PGGDD
656
LSKSP
661
EEKKT
666
ATQLH
671
SKRRP
676
KICGP
681
RYGET
686
KEKDI
691
DWGKR
696
CVDKF
701
DIIGI
706
IGEGT
711
YGQVY
716
KARDK
721
DTGEM
726
VALKK
731
VRLDN
736
EKEGF
741
PITAI
746
REIKI
751
LRQLT
756
HQSII
761
NMKEI
766
VTDKE
771
DALDF
776
KKDKG
781
AFYLV
786
FEYMD
791
HDLMG
796
LLESG
801
LVHFN
806
ENHIK
811
SFMRQ
816
LMEGL
821
DYCHK
826
KNFLH
831
RDIKC
836
SNILL
841
NNRGQ
846
IKLAD
851
FGLAR
856
LYSSE
861
ESAWL
866
MLIWE
871
KVIFI
876
WRILL
881
MQMSA
886
GSFGD
891
SSRPY
896
TNKVI
901
TLWYR
906
PPELL
911
LGEER
916
YTPAI
921
DVWSC
926
GCILG
931
ELFTK
936
KPIFQ
941
ANQEL
946
AQLEL
951
ISRIC
956
GSPCP
961
AVWPD
966
VIKLP
971
YFNTM
976
KPKKQ
981
YRRKL
986
REEFV
991
FIPAA
996
ALDLF
1001
DYMLA
1006
LDPSK
1011
RCTAE
1016
QALQC
1021
EFLRD
1026
VEPSK
1031
MPPPD
1036
LPLWQ
1041
DCHEL
1046
WSKKR
1051
RRQKQ
1056
MGMTD
1061
DVSTI
1066
KAPRK
1071
DLSLG
1076
LDDSR
1081
TNTPQ
1086
GVLPS
1091
SQLKS
1096
QGSSN
1101
VAPVK
1106
TGPGQ
1111
HLNHS
1116
ELAIL
1121
LNLLQ
1126
SKTSV
1131
NMADF
1136
VQVLN
1141
IKVNS
1146
ETQQQ
1151
LNKIN
1156
LPAGI
1161
LATGE
1166
KQTDP
1171
STPQQ
1176
ESSKP
1181
LGGIQ
1186
PSSQT
1191
IQPKV
1196
ETDAA
1201
QAAVQ
1206
SAFAV
1211
LLTQL
1216
IKAQQ
1221
SKQKD
1226
VLLEE
1231
RENGS
1236
GHEAS
1241
LQLRP
1246
PPEPS
1251
TPVSG
1256
QDDLI
1261
QHQDM
1266
RILEL
1271
TPEPD
1276
RPRIL
1281
PPDQR
1286
PPEPP
1291
EPPPV
1296
TEEDL
1301
DYRTE
1306
NQHVP
1311
TTSSS
1316
LTDPH
1321
AGVKA
1326
ALLQL
1331
LAQHQ
1336
PQDDP
1341
KREGG
1346
IDYQA
1351
GDTYV
1356
STSDY
1361
KDNFG
1366
SSSFS
1371
SAPYV
1376
SNDGL
1381
GSSSA
1386
PPLER
1391
RSFIG
1396
NSDIQ
1401
SLDNY
1406
STASS
1411
HSGGP
1416
PQPSA
1421
FSESF
1426
PSSVA
1431
GYGDI
1436
YLNAG
1441
PMLFS
1446
GDKDH
1451
RFEYS
1456
HGPIA
1461
VLANS
1466
SDPST
1471
GPEST
1476
HPLPA
1481
KMHNY
1486
NYGGN
1491
LQENP
1496
SGPSL
1501
MHGQT
1506
WTSPA
1511
QGPGY
1516
SQGYR
1521
GHIST
1526
STGRG
1531
RGRGL
1536
PY
1541
Mutation Information
DNA mutation:
None
Peptide Range:
853 ~ 873
Mut AA position:
857 (5 in Wild Type peptide)
Alignment
Wild Type:
"-----LADFGLARLY------
||||.|||||
Mutant:
RGQIKLADFRLARLYSSEESR"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) CDK13
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay