Immunogenicity 4460
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF648
Transcript ID
NM_001009992
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (568 aa)
MAQVD
1
SQDRW
6
GEASP
11
LSSLT
16
EEAHD
21
TQMLS
26
MNLES
31
DDEDG
36
GEAEK
41
EGTAD
46
PVACP
51
RGSSP
56
VTHEN
61
PDLPW
66
PHPLG
71
KEEEK
76
FSDSS
81
SAGGM
86
GQKPV
91
EMSGK
96
ASWSR
101
DVTKI
106
NETQG
111
SPGAS
116
RALGS
121
LPSGL
126
AHKLL
131
GQMQP
136
LGDRL
141
PAGDD
146
GYSGA
151
NQDAV
156
LDVPP
161
SFPSN
166
GKYLC
171
AHKSV
176
DTSAG
181
NSSLL
186
CFPRP
191
GSNWD
196
LPTQE
201
THTPA
206
QASAT
211
PASLA
216
AAVLA
221
KARNS
226
RKVQN
231
QAGRR
236
EGGEA
241
EARPY
246
RCLRG
251
GRAFQ
256
KPSKP
261
LSPAE
266
TRGGA
271
AKRYA
276
CELCG
281
KAYSH
286
RGTLQ
291
QHRRL
296
HTGER
301
PYQCS
306
FCDKA
311
YTWSS
316
DHRKH
321
IRTHT
326
GEKPY
331
PCPDC
336
GKAFV
341
RSSDL
346
RKHQR
351
NMHSN
356
NKPFP
361
CSECG
366
LTFNK
371
PLSLL
376
RHQRT
381
HLGAK
386
PFRCP
391
ACDRE
396
FAVAS
401
RMVEH
406
QRVHS
411
GERPF
416
PCPTC
421
GKCFT
426
KSSNL
431
SEHQT
436
LHTGQ
441
RPFKC
446
ADCGV
451
AFAQP
456
SRLVR
461
HQRIH
466
TGERP
471
FPCTQ
476
CGQAF
481
ARSST
486
LKRHQ
491
QIHSG
496
EKGFL
501
CAECG
506
RAFRI
511
ASELA
516
QHIRM
521
HNGER
526
PYQCE
531
DCGQA
536
FTRSN
541
HLQRH
546
RAKHG
551
TCKKE
556
PIPSS
561
SDE
566
Mutation Information
DNA mutation:
None
Peptide Range:
455 ~ 479
Mut AA position:
467 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAFAQPSRLVRHQRIHTGERPFPCT
||||||||||||.||||||||||||
Mutant:
VAFAQPSRLVRHHRIHTGERPFPCT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ZNF648
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay