Immunogenicity 447

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
KRIT1
Transcript ID
None
HLA INFO
A*66:01
TCR INFO

No TCR info found!

T cell Tumor cell A*66:01
sequence
Full length protein sequence (736 aa)
MGNPE
1
NIEDA
6
YVAVI
11
RPKNT
16
ASLNS
21
REYRA
26
KSYEI
31
LLHEV
36
PIEGQ
41
KKKRK
46
KVLLE
51
TKLQG
56
NSEIT
61
QGILD
66
YVVET
71
TKPIS
76
PANQG
81
IRGKR
86
VVLMK
91
KFPLD
96
GEKMG
101
REASL
106
FIVPS
111
VVKDN
116
TKYTY
121
TPGCP
126
IFYCL
131
QDIMR
136
VCSES
141
STHFA
146
TLTAR
151
MLIAL
156
DKWLD
161
ERHAQ
166
SHFIP
171
ALFRP
176
SPLER
181
IKTNV
186
INPAY
191
ATESG
196
QTENS
201
LHMGY
206
SALEI
211
KSKML
216
ALEKA
221
DTCIY
226
NPLFG
231
SDLQY
236
TNRVD
241
KVVIN
246
PYFGL
251
GAPDY
256
SKIQI
261
PKQEK
266
WQRSM
271
SSVTE
276
DKERQ
281
WVDDF
286
PLHRS
291
ACEGD
296
SELLS
301
RLLSE
306
RFSVN
311
QLDSD
316
HWAPI
321
HYACW
326
YGKVE
331
ATRIL
336
LEKGK
341
CNPNL
346
LNGQL
351
SSPLH
356
FAAGG
361
GHAEI
366
VQILL
371
NHPET
376
DRHIT
381
DQQGR
386
SPLNI
391
CEENK
396
QNNWE
401
EAAKL
406
LKEAI
411
NKPYE
416
KVRIY
421
RMDGS
426
YRSVE
431
LKHGN
436
NTTVQ
441
QIMEG
446
MRLSQ
451
ETQQY
456
FTIWI
461
CSENL
466
SLQLK
471
PYHKP
476
LQHVR
481
DWPEI
486
LAELT
491
NLDPQ
496
RETPQ
501
LFLRR
506
DVRLP
511
LEVEK
516
QIEDP
521
LAILI
526
LFDEA
531
RYNLL
536
KGFYT
541
APDAK
546
LITLA
551
SLLLQ
556
IVYGN
561
YESKK
566
HKQGF
571
LNEEN
576
LKSIV
581
PVTKL
586
KSKAP
591
HWTNR
596
ILHEY
601
KNLST
606
SEGVS
611
KEMHH
616
LQRMF
621
LQNCW
626
EIPTY
631
GAAFF
636
TGQIF
641
TKASP
646
SNHKV
651
IPVYV
656
GVNIK
661
GLHLL
666
NMETK
671
ALLIS
676
LKYGC
681
FMWQL
686
GDTDT
691
CFQIH
696
SMENK
701
MSFIV
706
HTKQA
711
GLVVK
716
LLMKL
721
NGQLM
726
PTERN
731
S
736
Mutation Information
DNA mutation:
None
Peptide Range:
597 ~ 620
Mut AA position:
600 (4 in Wild Type peptide)
Alignment
Wild Type:
"---------WTNRILHEY------
|||.|||||
Mutant:
TKLKSKAPHWTNCILHEYKNLSTS"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) KRIT1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay