Immunogenicity 448
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
COL22A1
Transcript ID
None
HLA INFO
A*23:01
TCR INFO
No TCR info found!
Full length protein sequence (1606 aa)
MAGLR
1
GNAVA
6
GLLWM
11
LLLWS
16
GGGGC
21
QAQRA
26
GCKSV
31
HYDLV
36
FLLDT
41
SSSVG
46
KEDFE
51
KVRQW
56
VANLV
61
DTFEV
66
GPDRT
71
RVGVV
76
RYSDR
81
PTTAF
86
ELGLF
91
GSQEE
96
VKAAA
101
RRLAY
106
HGGNT
111
NTGDA
116
LRYIT
121
ARSFS
126
PHAGG
131
RPRDR
136
AYKQV
141
AILLT
146
DGRSQ
151
DLVLD
156
AAAAA
161
HRAGI
166
RIFAV
171
GVGEA
176
LKEEL
181
EEIAS
186
EPKSA
191
HVFHV
196
SDFNA
201
IDKIR
206
GKLRR
211
RLCEN
216
VLCPS
221
VRVEG
226
DRFKH
231
TNGGT
236
KEITG
241
FDLMD
246
LFSVK
251
EILGK
256
RENGA
261
QSSYV
266
RMGSF
271
PVVQS
276
TEDVF
281
PQGLP
286
DEYAF
291
VTTFR
296
FRKTS
301
RKEDW
306
YIWQV
311
IDQYS
316
IPQVS
321
IRLDG
326
ENKAV
331
EYNAV
336
GAMKD
341
AVRVV
346
FRGSR
351
VNDLF
356
DRDWH
361
KMALS
366
IQAQN
371
VSLHI
376
DCALV
381
QTLPI
386
EEREN
391
IDIQG
396
KTVIG
401
KRLYD
406
SVPID
411
FDLQR
416
IVIYC
421
DSRHA
426
ELETC
431
CDIPS
436
GPCQV
441
TVVTE
446
PPPPP
451
PPQRP
456
PTPGS
461
EQIGF
466
LKTIN
471
CSCPA
476
GEKGE
481
MGVAG
486
PMGLP
491
GPKGD
496
IGAIG
501
PVGAP
506
GPKGE
511
KGDVG
516
IGPFG
521
QGEKG
526
EKGSL
531
GLPGP
536
PGRDG
541
SKGMR
546
GEPGE
551
LGEPG
556
LPGEV
561
GMRGP
566
QGPPG
571
LPGPP
576
GRVGA
581
PGLQG
586
ERGEK
591
GTRGE
596
KGERG
601
LDGFP
606
GKPGD
611
TGQQG
616
RPGPS
621
GVAGP
626
QGEKG
631
DVGPA
636
GPPGV
641
PGSVV
646
QQEGL
651
KGEQG
656
APGPR
661
GHQGA
666
PGPPG
671
ARGPI
676
GPEGR
681
DGPPG
686
LQGLR
691
GKKGD
696
MGPPG
701
IPGLL
706
GLQGP
711
PGPPG
716
VPGPP
721
GPGGS
726
PGLPG
731
EIGFP
736
GKPGP
741
PGPTG
746
PPGKD
751
GPNGP
756
PGPPG
761
TKGEP
766
GERGE
771
DGLPG
776
KPGLR
781
GEIGE
786
QGLAG
791
RPGEK
796
GEAGL
801
PGAPG
806
FPGVR
811
GEKGD
816
QGEKG
821
ELGLP
826
GLKGD
831
RGEKG
836
EAGPA
841
GPPGL
846
PGTTS
851
LFTPH
856
PRMPG
861
EQGPK
866
GEKGD
871
PGLPG
876
EPGLQ
881
GRPGE
886
LGPQG
891
PTGPP
896
GAKGQ
901
EGAHG
906
APGAA
911
GNPGA
916
PGHVG
921
APGPS
926
GPPGS
931
VGAPG
936
LRGTP
941
GKDGE
946
RGEKG
951
AAGEE
956
GSPGP
961
VGPRG
966
DPGAP
971
GLPGP
976
PGKGK
981
DGEPG
986
LRGSP
991
GLPGP
996
LGTKG
1001
DRGAP
1006
GIPGS
1011
PGSRG
1016
DPGIG
1021
VAGPP
1026
GPSGP
1031
PGDKG
1036
SPGSR
1041
GLPGF
1046
PGPQG
1051
PAGRD
1056
GAPGN
1061
PGERG
1066
PPGKP
1071
GLSSL
1076
LSPGD
1081
INLLA
1086
KDVCN
1091
DCPPG
1096
PPGLP
1101
GLPGF
1106
KGDKG
1111
VPGKP
1116
GREGT
1121
EGKKG
1126
EAGPP
1131
GLPGP
1136
PGIAG
1141
PQGSQ
1146
GERGA
1151
DGEVG
1156
QKGDQ
1161
GHPGV
1166
PGFMG
1171
PPGNP
1176
GPPGA
1181
DGIAG
1186
AAGPP
1191
GIQGS
1196
PGKEG
1201
PPGPQ
1206
GPSGL
1211
PGIPG
1216
EEGKE
1221
GRDGK
1226
PGPPG
1231
EPGKA
1236
GEPGL
1241
PGPEG
1246
ARGPP
1251
GFKGH
1256
TGDSG
1261
APGPR
1266
GESGA
1271
MGLPG
1276
QEGLP
1281
GKDGD
1286
TGPTG
1291
PQGPQ
1296
GPRGP
1301
PGKNG
1306
SPGSP
1311
GEPGP
1316
SGTPG
1321
QKGSK
1326
GENGS
1331
PGLPG
1336
FLGPR
1341
GPPGE
1346
PGEKG
1351
VPGKE
1356
GVPGK
1361
PGEPG
1366
FKGER
1371
GDPGI
1376
KGDKG
1381
PPGGK
1386
GQPGD
1391
PGIPG
1396
HKGHT
1401
GLMGP
1406
QGLPG
1411
ENGPV
1416
GPPGP
1421
PGQPG
1426
FPGLR
1431
GESPS
1436
METLR
1441
RLIQE
1446
ELGKQ
1451
LETRL
1456
AYLLA
1461
QMPPA
1466
YMKSS
1471
QGRPG
1476
PPGPP
1481
GKDGL
1486
PGRAG
1491
PMGEP
1496
GRPGQ
1501
GGLEG
1506
PSGPI
1511
GPKGE
1516
RGAKG
1521
DPGAP
1526
GVGLR
1531
GEMGP
1536
PGIPG
1541
QPGEP
1546
GYAKD
1551
GLPGI
1556
PGPQG
1561
ETGPA
1566
GHPGL
1571
PGPPG
1576
PPGQC
1581
DPSQC
1586
AYFAS
1591
LAARP
1596
GNVKG
1601
P
1606
Mutation Information
DNA mutation:
None
Peptide Range:
287 ~ 309
Mut AA position:
291 (5 in Wild Type peptide)
Alignment
Wild Type:
"------------QGLPDEYAF--
||||.||||
Mutant:
FPVVQSTEDVFPQGLPNEYAFVT"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) COL22A1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay