Immunogenicity 4485

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZFP28
Transcript ID
NM_020828
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (868 aa)
MRGAA
1
SASVR
6
EPTPL
11
PGRGA
16
PRTKP
21
RAGRG
26
PTVGT
31
PATLA
36
LPARG
41
RPRSR
46
NGLAS
51
KGQRG
56
AAPTG
61
PGHRA
66
LPSRD
71
TALPQ
76
ERNKK
81
LEAVG
86
TGIEP
91
KAMSQ
96
GLVTF
101
GDVAV
106
DFSQE
111
EWEWL
116
NPIQR
121
NLYRK
126
VMLEN
131
YRNLA
136
SLGLC
141
VSKPD
146
VISSL
151
EQGKE
156
PWTVK
161
RKMTR
166
AWCPD
171
LKAVW
176
KIKEL
181
PLKKD
186
FCEGK
191
LSQAV
196
ITERL
201
TSYNL
206
EYSLL
211
GEHWD
216
YDALF
221
ETQPG
226
LVTIK
231
NLAVD
236
FRQQL
241
HPAQK
246
NFCKN
251
GIWEN
256
NSDLG
261
SAGHC
266
VAKPD
271
LVSLL
276
EQEKE
281
PWMVK
286
RELTG
291
SLFSG
296
QRSVH
301
ETQEL
306
FPKQD
311
SYAEG
316
VTDRT
321
SNTKL
326
DCSSF
331
RENWD
336
SDYVF
341
GRKLA
346
VGQET
351
QFRQE
356
PITHN
361
KTLSK
366
ERERT
371
YNKSG
376
RWFYL
381
DDSEE
386
KVHNR
391
DSIKN
396
FQKSS
401
VVIKQ
406
TGIYA
411
GKKLF
416
KCNEC
421
KKTFT
426
QSSSL
431
TVHQR
436
IHTGE
441
KPYKC
446
NECGK
451
AFSDG
456
SSFAR
461
HQRCH
466
TGKKP
471
YECIE
476
CGKAF
481
IQNTS
486
LIRHW
491
RYYHT
496
GEKPF
501
DCIDC
506
GKAFS
511
DHIGL
516
NQHRR
521
IHTGE
526
KPYKC
531
DVCHK
536
SFRYG
541
SSLTV
546
HQRIH
551
TGEKP
556
YECDV
561
CRKAF
566
SHHAS
571
LTQHQ
576
RVHSG
581
EKPFK
586
CKECG
591
KAFRQ
596
NIHLA
601
SHLRI
606
HTGEK
611
PFECA
616
ECGKS
621
FSISS
626
QLATH
631
QRIHT
636
GEKPY
641
ECKVC
646
SKAFT
651
QKAHL
656
AQHQK
661
THTGE
666
KPYEC
671
KECGK
676
AFSQT
681
THLIQ
686
HQRVH
691
TGEKP
696
YKCME
701
CGKAF
706
GDNSS
711
CTQHQ
716
RLHTG
721
QRPYE
726
CIECG
731
KAFKT
736
KSSLI
741
CHRRS
746
HTGEK
751
PYECS
756
VCGKA
761
FSHRQ
766
SLSVH
771
QRIHS
776
GKKPY
781
ECKEC
786
RKTFI
791
QIGHL
796
NQHKR
801
VHTGE
806
RSYNY
811
KKSRK
816
VFRQT
821
AHLAH
826
HQRIH
831
TGESS
836
TCPSL
841
PSTSN
846
PVDLF
851
PKFLW
856
NPSSL
861
PSP
866
Mutation Information
DNA mutation:
None
Peptide Range:
118 ~ 142
Mut AA position:
130 (13 in Wild Type peptide)
Alignment
Wild Type:
"EWLNPIQRNLYRKVMLENYRNLASL
||||||||||||.||||||||||||
Mutant:
EWLNPIQRNLYRTVMLENYRNLASL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZFP28

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay