Immunogenicity 4492

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KLHL42
Transcript ID
NM_020782
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (505 aa)
MSAEE
1
MVQIR
6
LEDRC
11
YPVSK
16
RKLIE
21
QSDYF
26
RALYR
31
SGMRE
36
ALSQE
41
AGGPE
46
VQQLR
51
GLSAP
56
GLRLV
61
LDFIN
66
AGGAR
71
EGWLL
76
GPRGE
81
KGGGV
86
DEDEE
91
MDEVS
96
LLSEL
101
VEAAS
106
FLQVT
111
SLLQL
116
LLSQV
121
RLNNC
126
LEMYR
131
LAQVY
136
GLPDL
141
QEACL
146
RFMVV
151
HFHEV
156
LCKPQ
161
FHLLG
166
SPPQA
171
PGDVS
176
LKQRL
181
REARM
186
TGTPV
191
LVALG
196
DFLGG
201
PLAPH
206
PYQGE
211
PPSML
216
RYEEM
221
TERWF
226
PLANN
231
LPPDL
236
VNVRG
241
YGSAI
246
LDNYL
251
FIVGG
256
YRITS
261
QEISA
266
AHSYN
271
PSTNE
276
WLQVA
281
SMNQK
286
RSNFK
291
LVAVN
296
SKLYA
301
IGGQA
306
VSNVE
311
CYNPE
316
QDAWN
321
FVAPL
326
PNPLA
331
EFSAC
336
ECKGK
341
IYVIG
346
GYTTR
351
DRNMN
356
ILQYC
361
PSSDM
366
WTLFE
371
TCDVH
376
IRKQQ
381
MVSVE
386
ETIYI
391
VGGCL
396
HELGP
401
NRRSS
406
QSEDM
411
LTVQS
416
YNTVT
421
RQWLY
426
LKENT
431
SKSGL
436
NLTCA
441
LHNDG
446
IYIMS
451
RDVTL
456
STSLE
461
HRVFL
466
KYNIF
471
SDSWE
476
AFRRF
481
PAFGH
486
NLLVS
491
SLYLP
496
NKAET
501
Mutation Information
DNA mutation:
None
Peptide Range:
385 ~ 409
Mut AA position:
397 (13 in Wild Type peptide)
Alignment
Wild Type:
"QMVSVEETIYIVGGCLHELGPNRRS
||||||||||||.||||||||||||
Mutant:
QMVSVEETIYIVEGCLHELGPNRRS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KLHL42

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay