Immunogenicity 4501

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCDHGA8
Transcript ID
NM_032088
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (932 aa)
MAAPQ
1
SRPRR
6
GELIL
11
LCALL
16
GTLWE
21
IGRGQ
26
IRYSV
31
PEETD
36
KGSFV
41
GNISK
46
DLGLD
51
PRKLA
56
KHGVR
61
IVSRG
66
RTQLF
71
ALNPR
76
SGSLI
81
TAGRI
86
DREEL
91
CAQSP
96
RCLIN
101
INTLV
106
EDKGK
111
LFGVE
116
IEIID
121
INDNN
126
PKFQV
131
EDLEV
136
KINEI
141
AVPGA
146
RYPLP
151
EAVDP
156
DVGVN
161
SLQSY
166
QLSPN
171
HHFSL
176
DVQTG
181
DNGAI
186
NPELV
191
LERAL
196
DREEE
201
AAHHL
206
VLTAS
211
DGGKP
216
PRSST
221
VRIHV
226
TVLDT
231
NDNAP
236
VFPHP
241
IYRVK
246
VLENM
251
PPGTR
256
LLTVT
261
ASDPD
266
EGING
271
KVAYK
276
FRKIN
281
EKQTP
286
LFQLN
291
ENTGE
296
ISIAK
301
SLDYE
306
ECSFY
311
EMEIQ
316
AEDVG
321
ALLGR
326
TKLLI
331
SVEDV
336
NDNRP
341
EVIIT
346
SLFSP
351
VLENS
356
LPGTV
361
IAFLS
366
VHDQD
371
SGKNG
376
QVVCY
381
TRDNL
386
PFKLE
391
KSIGN
396
YYRLV
401
TRKYL
406
DRENV
411
SIYNI
416
TVMAS
421
DLGTP
426
PLSTE
431
TQIAL
436
HVADI
441
NDNPP
446
TFPHA
451
SYSAY
456
ILENN
461
LRGAS
466
IFSLT
471
AHDPD
476
SQENA
481
QVTYS
486
VTEDT
491
LQGAP
496
LSSYI
501
SINSD
506
TGVLY
511
ALQSF
516
DYEQI
521
RDLQL
526
LVTAS
531
DSGDP
536
PLSSN
541
MSLSL
546
FVLDQ
551
NDNAP
556
EILYP
561
ALPTD
566
GSTGV
571
ELAPR
576
SAERG
581
YLVTK
586
VVAVD
591
RDSGQ
596
NAWLS
601
YRLLK
606
ASEPG
611
LFSVG
616
LHTGE
621
VRTAR
626
ALLDR
631
DALKQ
636
SLVVA
641
VQDHG
646
QPPLS
651
ATVTL
656
TVAVA
661
DSIPE
666
VLTEL
671
GSLKP
676
SVDPN
681
DSSLT
686
LYLVV
691
AVAAI
696
SCVFL
701
AFVAV
706
LLGLR
711
LRRWH
716
KSRLL
721
QDSGG
726
RLVGV
731
PASHF
736
VGVEE
741
VQAFL
746
QTYSQ
751
EVSLT
756
ADSRK
761
SHLIF
766
PQPNY
771
ADMLI
776
SQEGC
781
EKNDS
786
LLTSV
791
DFHEY
796
KNEAD
801
HGQQA
806
PPNTD
811
WRFSQ
816
AQRPG
821
TSGSQ
826
NGDDT
831
GTWPN
836
NQFDT
841
EMLQA
846
MILAS
851
ASEAA
856
DGSST
861
LGGGA
866
GTMGL
871
SARYG
876
PQFTL
881
QHVPD
886
YRQNV
891
YIPGS
896
NATLT
901
NAAGK
906
RDGKA
911
PAGGN
916
GNKKK
921
SGKKE
926
KK
931
Mutation Information
DNA mutation:
None
Peptide Range:
412 ~ 436
Mut AA position:
424 (13 in Wild Type peptide)
Alignment
Wild Type:
"RENVSIYNITVMASDLGTPPLSTET
||||||||||||.||||||||||||
Mutant:
RENVSIYNITVMSSDLGTPPLSTET"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PCDHGA8

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay