Immunogenicity 4509

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
INMT
Transcript ID
NM_006774
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (263 aa)
MKGGF
1
TGGDE
6
YQKHF
11
LPRDY
16
LATYY
21
SFDGS
26
PSPEA
31
EMLKF
36
NLECL
41
HKTFG
46
PGGLQ
51
GDTLI
56
DIGSG
61
PTIYQ
66
VLAAC
71
DSFQD
76
ITLSD
81
FTDRN
86
REELE
91
KWLKK
96
EPGAY
101
DWTPA
106
VKFAC
111
ELEGN
116
SGRWE
121
EKEEK
126
LRAAV
131
KRVLK
136
CDVHL
141
GNPLA
146
PAVLP
151
LADCV
156
LTLLA
161
MECAC
166
CSLDA
171
YRAAL
176
CNLAS
181
LLKPG
186
GHLVT
191
TVTLR
196
LPSYM
201
VGKRE
206
FSCVA
211
LEKEE
216
VEQAV
221
LDAGF
226
DIEQL
231
LHSPQ
236
SYSVT
241
NAANN
246
GVCFI
251
VARKK
256
PGP
261
Mutation Information
DNA mutation:
None
Peptide Range:
79 ~ 103
Mut AA position:
91 (13 in Wild Type peptide)
Alignment
Wild Type:
"QDITLSDFTDRNREELEKWLKKEPG
||||||||||||.||||||||||||
Mutant:
QDITLSDFTDRNWEELEKWLKKEPG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) INMT

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay