Immunogenicity 452
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DNASE1L1
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (302 aa)
MHYPT
1
ALLFL
6
ILANG
11
AQAFR
16
ICAFN
21
AQRLT
26
LAKVA
31
REQVM
36
DTLVR
41
ILARC
46
DIMVL
51
QEVVD
56
SSGSA
61
IPLLL
66
RELNR
71
FDGSG
76
PYSTL
81
SSPQL
86
GRSTY
91
METYV
96
YFYRS
101
HKTQV
106
LSSYV
111
YNDED
116
DVFAR
121
EPFVA
126
QFSLP
131
SNVLP
136
SLVLV
141
PLHTT
146
PKAVE
151
KELNA
156
LYDVF
161
LEVSQ
166
HWQSK
171
DVILL
176
GDFNA
181
DCASL
186
TKKRL
191
DKLEL
196
RTEPG
201
FHWVI
206
ADGED
211
TTVRA
216
STHCT
221
YDRVV
226
LHGER
231
CRSLL
236
HTAAA
241
FDFPT
246
SFQLT
251
EEEAL
256
NISDH
261
YPVEV
266
ELKLS
271
QAHSV
276
QPLSL
281
TVLLL
286
LSLLS
291
PQLCP
296
AA
301
Mutation Information
DNA mutation:
None
Peptide Range:
133 ~ 152
Mut AA position:
140 (8 in Wild Type peptide)
Alignment
Wild Type:
"SLPSNVLPSL----------
|||||||.||
Mutant:
SLPSNVLSSLVLVPLHTTPK"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) DNASE1L1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay