Immunogenicity 453
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ARHGAP29
Transcript ID
None
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (1261 aa)
MIAHK
1
QKKTK
6
KKRAW
11
ASGQL
16
STDIT
21
TSEMG
26
LKSLS
31
SNSIF
36
DPDYI
41
KELVN
46
DIRKF
51
SHMLL
56
YLKEA
61
IFSDC
66
FKEVI
71
HIRLE
76
ELLRV
81
LKSIM
86
NKHQN
91
LNSVD
96
LQNAA
101
EMLTA
106
KVKAV
111
NFTEV
116
NEENK
121
NDLFQ
126
EVFSS
131
IETLA
136
FTFGN
141
ILTNF
146
LMGDV
151
GNDSL
156
LRLPV
161
SRETK
166
SFENV
171
SVESV
176
DSSSE
181
KGNFS
186
PLELD
191
NVLLK
196
NTDSI
201
ELALS
206
YAKTW
211
SKYTK
216
NIVSW
221
VEKKL
226
NLELE
231
STRNM
236
VKLAE
241
ATRTN
246
IGIQE
251
FMPLQ
256
SLFTN
261
ALLND
266
IESSH
271
LLQQT
276
IAALQ
281
ANKFV
286
QPLLG
291
RKNEM
296
EKQRK
301
EIKEL
306
WKQEQ
311
NKMLE
316
AENAL
321
KKAKL
326
LCMQR
331
QDEYE
336
KAKSS
341
MFRAE
346
EEHLS
351
SSGGL
356
AKNLN
361
KQLEK
366
KRRLE
371
EEALQ
376
KVEEA
381
NELYK
386
VCVTN
391
VEERR
396
NDLEN
401
TKREI
406
LAQLR
411
TLVFQ
416
CDLTL
421
KAVTV
426
NLFHM
431
QHLQA
436
ASLAD
441
SLQSL
446
CDSAK
451
LYDPG
456
QEYSE
461
FVKAT
466
NSTEE
471
EKVDG
476
NVNKH
481
LNSSQ
486
PSGFG
491
PANSL
496
EDVVR
501
LPDSS
506
NKIEE
511
DRCSN
516
SADIT
521
GPSFI
526
RSWTF
531
GMFSD
536
SESTG
541
GSSES
546
RSLDS
551
ESISP
556
GDFHR
561
KLPRT
566
PSSGT
571
MSSAD
576
DLDER
581
EPPSP
586
SETGP
591
NSLGT
596
FKKTL
601
MSKAA
606
LTHKF
611
RKLRS
616
PTKCR
621
DCEGI
626
VVFQG
631
VECEE
636
CLLVC
641
HRKCL
646
ENLVI
651
ICGHQ
656
KLPGK
661
IHLFG
666
AEFTQ
671
VAKKE
676
PDGIP
681
FILKI
686
CASEI
691
ENRAL
696
CLQGI
701
YRVCG
706
NKIKT
711
EKLCQ
716
ALENG
721
MHLVD
726
ISEFS
731
SHDIC
736
DVLKL
741
YLRQL
746
PEPFI
751
LFRLY
756
KEFID
761
LAKEI
766
QHVNE
771
EQETK
776
KNSLE
781
DKKWP
786
NMCIE
791
INRIL
796
LKSKD
801
LLRQL
806
PASNF
811
NSLHF
816
LIVHL
821
KRVVD
826
HAEEN
831
KMNSK
836
NLGVI
841
FGPSL
846
IRPRP
851
TTAPI
856
TISSL
861
AEYSN
866
QARLV
871
EFLIT
876
YSQKI
881
FDGSL
886
QPQDV
891
MCSIG
896
VVDQG
901
CFPKP
906
LLSPE
911
ERDIE
916
RSMKS
921
LFFSS
926
KEDIH
931
TSESE
936
SKIFE
941
RATSF
946
EESER
951
KQNAL
956
GKCDA
961
CLSDK
966
AQLLL
971
DQEAE
976
SASQK
981
IEDGK
986
TPKPL
991
SLKSD
996
RSTNN
1001
VERHT
1006
PRTKI
1011
RPVSL
1016
PVDRL
1021
LLASP
1026
PNERN
1031
GRNMG
1036
NVNLD
1041
KFCKN
1046
PAFEG
1051
VNRKD
1056
AATTV
1061
CSKFN
1066
GFDQQ
1071
TLQKI
1076
QDKQY
1081
EQNSL
1086
TAKTT
1091
MIMPS
1096
ALQEK
1101
GVTTS
1106
LQISG
1111
DHSIN
1116
ATQPS
1121
KPYAE
1126
PVRSV
1131
REASE
1136
RRSSD
1141
SYPLA
1146
PVRAP
1151
RTLQP
1156
QHWTT
1161
FYKPH
1166
APIIS
1171
IRGNE
1176
EKPAS
1181
PSAAV
1186
PPGTD
1191
HDPHG
1196
LVVKS
1201
MPDPD
1206
KASAC
1211
PGQAT
1216
GQPKE
1221
DSEEL
1226
GLPDV
1231
NPMCQ
1236
RPRLK
1241
RMQQF
1246
EDLEG
1251
EIPQF
1256
V
1261
Mutation Information
DNA mutation:
None
Peptide Range:
669 ~ 694
Mut AA position:
670 (2 in Wild Type peptide)
Alignment
Wild Type:
"-----------FGAEFTQVA------
|.|||||||
Mutant:
GHQKLPGKIHLFEAEFTQVAKKEPDG"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) ARHGAP29
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay