Immunogenicity 454
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DNMBP
Transcript ID
None
HLA INFO
A*01:03
TCR INFO
No TCR info found!
Full length protein sequence (1577 aa)
MEAGS
1
VVRAI
6
FDFCP
11
SVSEE
16
LPLFV
21
GDIIE
26
VLAVV
31
DEFWL
36
LGKKE
41
DVTGQ
46
FPSSF
51
VEIVT
56
IPSLK
61
EGERL
66
FVCIC
71
EFTSQ
76
ELDNL
81
PLHRG
86
DLVIL
91
DGIPT
96
AGWLQ
101
GRSCW
106
GARGF
111
FPSSC
116
VRELC
121
LSSQS
126
RQWHS
131
QSALF
136
QIPEY
141
SMGQA
146
RALMG
151
LSAQL
156
DEELD
161
FREGD
166
VITII
171
GVPEP
176
GWFEG
181
ELEGR
186
RGIFP
191
EGFVE
196
LLGPL
201
RTVDE
206
SVSSG
211
NQDDC
216
IVNGE
221
VDTPV
226
GEEEI
231
GPDED
236
EEEPG
241
TYGVA
246
LYRFQ
251
ALEPN
256
ELDFE
261
VGDKI
266
RILAT
271
LEDGW
276
LEGSL
281
KGRTG
286
IFPYR
291
FVKLC
296
PDTRV
301
EETMA
306
LPQEG
311
SLARI
316
PETSL
321
DCLEN
326
TLGVE
331
EQRHE
336
TSDHE
341
AEEPD
346
CIISE
351
APTSP
356
LGHLT
361
SEYDT
366
DRNSY
371
QDEDT
376
AGGPP
381
RSPGV
386
EWEMP
391
LATDS
396
PTSDP
401
TEVVN
406
GISSQ
411
PQVPF
416
HPNLQ
421
KSQYY
426
STVGG
431
SHPHS
436
EQYPD
441
LLPLE
446
ARTRD
451
YASLP
456
PKRMY
461
SQLKT
466
LQKPV
471
LPLYR
476
GSSVS
481
ASRVV
486
KPRQS
491
SPQLH
496
NLASY
501
TKKHH
506
TSSVY
511
SISER
516
LEMKP
521
GPQAQ
526
GLVME
531
AATHS
536
QGDGS
541
TDLDS
546
KLTQQ
551
LIEFE
556
KSLAG
561
PGTEP
566
DKILR
571
HFSIM
576
DFNSE
581
KDIVR
586
GSSKL
591
ITEQE
596
LPERR
601
KALRP
606
PPPRP
611
CTPVS
616
TSPHL
621
LVDQN
626
LKPAP
631
PLVVR
636
PSRPA
641
PLPPS
646
AQQRT
651
NAVSP
656
KLLSR
661
HRPTC
666
ETLEK
671
EGPGH
676
MGRSL
681
DQTSP
686
CPLVL
691
VRIEE
696
MERDL
701
DMYSR
706
AQEEL
711
NLMLE
716
EKQDE
721
SSRAE
726
TLEDL
731
KFCES
736
NIESL
741
NMELQ
746
QLREM
751
TLLSS
756
QSSSL
761
VAPSG
766
SVSAE
771
NPEQR
776
MLEKR
781
AKVIE
786
ELLQT
791
ERDYI
796
RDLEM
801
CIERI
806
MVPMQ
811
QAQVP
816
NIDFE
821
GLFGN
826
MQMVI
831
KVSKQ
836
LLAAL
841
EISDA
846
VGPVF
851
LGHRD
856
ELEGT
861
YKIYC
866
QNHDE
871
AIALL
876
EIYEK
881
DEKIQ
886
KHLQD
891
SLADL
896
KSLYN
901
EWGCT
906
NYINL
911
GSFLI
916
KPVQR
921
VMRYP
926
LLLME
931
LLNST
936
PESHP
941
DKVPL
946
TNAVL
951
AVKEI
956
NVNIN
961
EYKRR
966
KDLVL
971
KYRKG
976
DEDSL
981
MEKIS
986
KLNIH
991
SIIKK
996
SNRVS
1001
SHLKH
1006
LTGFA
1011
PQIKD
1016
EVFEE
1021
TEKNF
1026
RMQER
1031
LIKSF
1036
IRDLS
1041
LYLQH
1046
IRESA
1051
CVKVV
1056
AAVSM
1061
WDVCM
1066
ERGHR
1071
DLEQF
1076
ERVHR
1081
YISDQ
1086
LFTNF
1091
KERTE
1096
RLVIS
1101
PLNQL
1106
LSMFT
1111
GPHKL
1116
VQKRF
1121
DKLLD
1126
FYNCT
1131
ERAEK
1136
LKDKK
1141
TLEEL
1146
QSARN
1151
NYEAL
1156
NAQLL
1161
DELPK
1166
FHQYA
1171
QGLFT
1176
NCVHG
1181
YAEAH
1186
CDFVH
1191
QALEQ
1196
LKPLL
1201
SLLKV
1206
AGREG
1211
NLIAI
1216
FHEEH
1221
SRVLQ
1226
QLQVF
1231
TFFPE
1236
SLPAT
1241
KKPFE
1246
RKTID
1251
RQSAR
1256
KPLLG
1261
LPSYM
1266
LQSEE
1271
LRASL
1276
LARYP
1281
PEKLF
1286
QAERN
1291
FNAAQ
1296
DLDVS
1301
LLEGD
1306
LVGVI
1311
KKKDP
1316
MGSQN
1321
RWLID
1326
NGVTK
1331
GFVYS
1336
SFLKP
1341
YNPRR
1346
SHSDA
1351
SVGSH
1356
SSTES
1361
EHGSS
1366
SPRFP
1371
RQNSG
1376
STLTF
1381
NPSSM
1386
AVSFT
1391
SGSCQ
1396
KQPQD
1401
ASPPP
1406
KECDQ
1411
GTLSA
1416
SLNPS
1421
NSESS
1426
PSRCP
1431
SDPDS
1436
TSQPR
1441
SGDSA
1446
DVARD
1451
VKQPT
1456
ATPRS
1461
YRNFR
1466
HPEIV
1471
GYSVP
1476
GRNGQ
1481
SQDLV
1486
KGCAR
1491
TAQAP
1496
EDRST
1501
EPDGS
1506
EAEGN
1511
QVYFA
1516
VYTFK
1521
ARNPN
1526
ELSVS
1531
ANQKL
1536
KILEF
1541
KDVTG
1546
NTEWW
1551
LAEVN
1556
GKKGY
1561
VPSNY
1566
IRKTE
1571
YT
1576
Mutation Information
DNA mutation:
None
Peptide Range:
413 ~ 437
Mut AA position:
421 (9 in Wild Type peptide)
Alignment
Wild Type:
"----SSQPQVPFH------------
||||||||.
Mutant:
VNGISSQPQVPFYPNLQKSQYYSTV"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) DNMBP
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay