Immunogenicity 455
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DTX4
Transcript ID
None
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (513 aa)
MEVGI
1
TIQHA
6
YEKQH
11
PWIDL
16
TSIGF
21
SYVID
26
FNTMG
31
QINRQ
36
TQRQR
41
RVRRR
46
LDLIY
51
PMVTG
56
TLPKA
61
QSWPV
66
SPGPA
71
TSPPM
76
SPCSC
81
PQCVL
86
VMSVK
91
AAVVN
96
GSTGP
101
LQLPV
106
TRKNM
111
PPPGV
116
VKLPP
121
LPGSG
126
AKPLD
131
STGTI
136
RGPLK
141
TAPSQ
146
VIRRQ
151
ASSMP
156
TGTTM
161
GSPAS
166
PPGPN
171
SKTGR
176
VALAT
181
LNRTN
186
LQRLA
191
IAQSR
196
VLIAS
201
GVPTV
206
PVKNL
211
NGSSP
216
VNPAL
221
AGITG
226
ILMSA
231
AGLPV
236
CLTRP
241
PKLVL
246
HPPPV
251
SKSEI
256
KSIPG
261
VSNTS
266
RKTTK
271
KQAKK
276
GKTPE
281
EVLKK
286
YLQKV
291
RHPPD
296
EDCTI
301
CMERL
306
TAPSG
311
YKGPQ
316
PTVKP
321
DLVGK
326
LSRCG
331
HVYHI
336
YCLVA
341
MYNNG
346
NKDGS
351
LQCPT
356
CKTIY
361
GVKTG
366
TQPPG
371
KMEYH
376
LIPHS
381
LPGHP
386
DCKTI
391
RIIYS
396
IPPGI
401
QGPEH
406
PNPGK
411
SFSAR
416
GFPRH
421
CYLPD
426
SEKGR
431
KVLKL
436
LLVAW
441
DRRLI
446
FAIGT
451
SSTTG
456
ESDTV
461
IWNEV
466
HHKTE
471
FGSNL
476
TGHGY
481
PDANY
486
LDNVL
491
AELAA
496
QGISE
501
DSTAQ
506
EKD
511
Mutation Information
DNA mutation:
None
Peptide Range:
108 ~ 133
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"----LPVTRKNMPP------------
|||||||||.
Mutant:
GPLQLPVTRKNMPLPGVVKLPPLPGS"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) DTX4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay