Immunogenicity 4558

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
H1FNT
Transcript ID
NM_181788
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (255 aa)
MEQAL
1
TGEAQ
6
SRWPR
11
RGGSG
16
AMAEA
21
PGPSG
26
ESRGH
31
SATQL
36
PAEKT
41
VGGPS
46
RGCSS
51
SVLRV
56
SQLVL
61
QAIST
66
HKGLT
71
LAALK
76
KELRN
81
AGYEV
86
RRKSG
91
RHEAP
96
RGQAK
101
ATLLR
106
VSGSD
111
AAGYF
116
RVWKV
121
PKPRR
126
KPGRA
131
RQEEG
136
TRAPW
141
RTPAA
146
PRSSR
151
RRRQP
156
LRKAA
161
RKARE
166
VWRRN
171
ARAKA
176
KANAR
181
ARRTR
186
RARPR
191
AKEPP
196
CARAK
201
EEAGA
206
TAADE
211
GRGQA
216
VKEDT
221
TPRSG
226
KDKRR
231
SSKPR
236
EEKQE
241
PKKPA
246
QRTIQ
251
Mutation Information
DNA mutation:
None
Peptide Range:
123 ~ 147
Mut AA position:
135 (13 in Wild Type peptide)
Alignment
Wild Type:
"WKVPKPRRKPGRARQEEGTRAPWRT
||||||||||||.||||||||||||
Mutant:
WKVPKPRRKPGRVRQEEGTRAPWRT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) H1FNT

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay