Immunogenicity 456

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PIK3R2
Transcript ID
None
HLA INFO
B*35:01
TCR INFO

No TCR info found!

T cell Tumor cell B*35:01
sequence
Full length protein sequence (728 aa)
MAGPE
1
GFQYR
6
ALYPF
11
RRERP
16
EDLEL
21
LPGDV
26
LVVSR
31
AALQA
36
LGVAE
41
GGERC
46
PQSVG
51
WMPGL
56
NERTR
61
QRGDF
66
PGTYV
71
EFLGP
76
VALAR
81
PGPRP
86
RGPRP
91
LPARP
96
RDGAP
101
EPGLT
106
LPDLP
111
EQFSP
116
PDVAP
121
PLLVK
126
LVEAI
131
ERTGL
136
DSESH
141
YRPEL
146
PAPRT
151
DWSLS
156
DVDQW
161
DTAAL
166
ADGIK
171
SFLLA
176
LPAPL
181
VTPEA
186
SAEAR
191
RALRE
196
AAGPV
201
GPALE
206
PPTLP
211
LHRAL
216
TLRFL
221
LQHLG
226
RVARR
231
APALG
236
PAVRA
241
LGATF
246
GPLLL
251
RAPPP
256
PSSPP
261
PGGAP
266
DGSEP
271
SPDFP
276
ALLVE
281
KLLQE
286
HLEEQ
291
EVAPP
296
ALPPK
301
PPKAK
306
PAPTV
311
LANGG
316
SPPSL
321
QDAEW
326
YWGDI
331
SREEV
336
NEKLR
341
DTPDG
346
TFLVR
351
DASSK
356
IQGEY
361
TLTLR
366
KGGNN
371
KLIKV
376
FHRDG
381
HYGFS
386
EPLTF
391
CSVVD
396
LINHY
401
RHESL
406
AQYNA
411
KLDTR
416
LLYPV
421
SKYQQ
426
DQIVK
431
EDSVE
436
AVGAQ
441
LKVYH
446
QQYQD
451
KSREY
456
DQLYE
461
EYTRT
466
SQELQ
471
MKRTA
476
IEAFN
481
ETIKI
486
FEEQG
491
QTQEK
496
CSKEY
501
LERFR
506
REGNE
511
KEMQR
516
ILLNS
521
ERLKS
526
RIAEI
531
HESRT
536
KLEQQ
541
LRAQA
546
SDNRE
551
IDKRM
556
NSLKP
561
DLMQL
566
RKIRD
571
QYLVW
576
LTQKG
581
ARQKK
586
INEWL
591
GIKNE
596
TEDQY
601
ALMED
606
EDDLP
611
HHEER
616
TWYVG
621
KINRT
626
QAEEM
631
LSGKR
636
DGTFL
641
IRESS
646
QRGCY
651
ACSVV
656
VDGDT
661
KHCVI
666
YRTAT
671
GFGFA
676
EPYNL
681
YGSLK
686
ELVLH
691
YQHAS
696
LVQHN
701
DALTV
706
TLAHP
711
VRAPG
716
PGPPP
721
AAR
726
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 19
Mut AA position:
5 (5 in Wild Type peptide)
Alignment
Wild Type:
"MAGPEGFQY----------
||||.||||
Mutant:
MAGPKGFQYRALYPFRRER"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) PIK3R2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay