Immunogenicity 458

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TLR3
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (904 aa)
MRQTL
1
PCIYF
6
WGGLL
11
PFGML
16
CASST
21
TKCTV
26
SHEVA
31
DCSHL
36
KLTQV
41
PDDLP
46
TNITV
51
LNLTH
56
NQLRR
61
LPAAN
66
FTRYS
71
QLTSL
76
DVGFN
81
TISKL
86
EPELC
91
QKLPM
96
LKVLN
101
LQHNE
106
LSQLS
111
DKTFA
116
FCTNL
121
TELHL
126
MSNSI
131
QKIKN
136
NPFVK
141
QKNLI
146
TLDLS
151
HNGLS
156
STKLG
161
TQVQL
166
ENLQE
171
LLLSN
176
NKIQA
181
LKSEE
186
LDIFA
191
NSSLK
196
KLELS
201
SNQIK
206
EFSPG
211
CFHAI
216
GRLFG
221
LFLNN
226
VQLGP
231
SLTEK
236
LCLEL
241
ANTSI
246
RNLSL
251
SNSQL
256
STTSN
261
TTFLG
266
LKWTN
271
LTMLD
276
LSYNN
281
LNVVG
286
NDSFA
291
WLPQL
296
EYFFL
301
EYNNI
306
QHLFS
311
HSLHG
316
LFNVR
321
YLNLK
326
RSFTK
331
QSISL
336
ASLPK
341
IDDFS
346
FQWLK
351
CLEHL
356
NMEDN
361
DIPGI
366
KSNMF
371
TGLIN
376
LKYLS
381
LSNSF
386
TSLRT
391
LTNET
396
FVSLA
401
HSPLH
406
ILNLT
411
KNKIS
416
KIESD
421
AFSWL
426
GHLEV
431
LDLGL
436
NEIGQ
441
ELTGQ
446
EWRGL
451
ENIFE
456
IYLSY
461
NKYLQ
466
LTRNS
471
FALVP
476
SLQRL
481
MLRRV
486
ALKNV
491
DSSPS
496
PFQPL
501
RNLTI
506
LDLSN
511
NNIAN
516
INDDM
521
LEGLE
526
KLEIL
531
DLQHN
536
NLARL
541
WKHAN
546
PGGPI
551
YFLKG
556
LSHLH
561
ILNLE
566
SNGFD
571
EIPVE
576
VFKDL
581
FELKI
586
IDLGL
591
NNLNT
596
LPASV
601
FNNQV
606
SLKSL
611
NLQKN
616
LITSV
621
EKKVF
626
GPAFR
631
NLTEL
636
DMRFN
641
PFDCT
646
CESIA
651
WFVNW
656
INETH
661
TNIPE
666
LSSHY
671
LCNTP
676
PHYHG
681
FPVRL
686
FDTSS
691
CKDSA
696
PFELF
701
FMINT
706
SILLI
711
FIFIV
716
LLIHF
721
EGWRI
726
SFYWN
731
VSVHR
736
VLGFK
741
EIDRQ
746
TEQFE
751
YAAYI
756
IHAYK
761
DKDWV
766
WEHFS
771
SMEKE
776
DQSLK
781
FCLEE
786
RDFEA
791
GVFEL
796
EAIVN
801
SIKRS
806
RKIIF
811
VITHH
816
LLKDP
821
LCKRF
826
KVHHA
831
VQQAI
836
EQNLD
841
SIILV
846
FLEEI
851
PDYKL
856
NHALC
861
LRRGM
866
FKSHC
871
ILNWP
876
VQKER
881
IGAFR
886
HKLQV
891
ALGSK
896
NSVH
901
Mutation Information
DNA mutation:
None
Peptide Range:
481 ~ 509
Mut AA position:
489 (9 in Wild Type peptide)
Alignment
Wild Type:
"---------SLQRLMLRRV----------
||||||||.|
Mutant:
TRNSFALVPSLQRLMLRKVALKNVDSSPS"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) TLR3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay