Immunogenicity 4597

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FRG2B
Transcript ID
NM_001080998
HLA INFO
A*30:02
TCR INFO

No TCR info found!

T cell Tumor cell A*30:02
sequence
Full length protein sequence (278 aa)
MGKGN
1
EDPDL
6
HCSSI
11
QCSTD
16
QPPFQ
21
QISFT
26
EKGSD
31
EKKPF
36
KEKGK
41
TAFSH
46
SSEKH
51
IQRQG
56
SEPNP
61
NKENS
66
EETKL
71
KAGNS
76
TAGSE
81
PESSS
86
YRENC
91
RKRKM
96
SSKDS
101
CQDTA
106
GNCPE
111
KECSL
116
SLNKK
121
SRSST
126
PVHNS
131
EIQET
136
CDAHH
141
RGRSR
146
ACTGR
151
SKRHR
156
SRALG
161
VQTPS
166
IRKSL
171
VTSVR
176
AMSEA
181
VYQDL
186
AQVWA
191
QQIHS
196
PLTCE
201
QLTLL
206
TRLRG
211
PLCAQ
216
VQTLY
221
SMATQ
226
AAYVF
231
PAESW
236
LVPAT
241
LPGPG
246
ESALD
251
REAHP
256
FPGQE
261
ITETV
266
SGSDE
271
AKL
276
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 21
Mut AA position:
9 (9 in Wild Type peptide)
Alignment
Wild Type:
"MGKGNEDPDLHCSSIQCSTDQPPFQ
||||||||.||||||||||||
Mutant:
MGKGNEDPNLHCSSIQCSTDQ----"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FRG2B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay