Immunogenicity 46
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
SLX4
Transcript ID
uc002cvq.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1834 aa)
MKLSV
1
NEAQL
6
GFYLG
11
SLSHL
16
SACPG
21
IDPRS
26
SEDQP
31
ESLKT
36
GQMMD
41
ESDED
46
FKELC
51
ASFFQ
56
RVKKH
61
GIKEV
66
SGERK
71
TQKAA
76
SNGTQ
81
IRSKL
86
KRTKQ
91
TATKT
96
KTLQG
101
PAEKK
106
PPSGS
111
QAPRT
116
KKQRV
121
TKWQA
126
SEPAH
131
SVNGE
136
GGVLA
141
SAPDP
146
PVLRE
151
TAQNT
156
QTGNQ
161
QEPSP
166
NLSRE
171
KTREN
176
VPNSD
181
SQPPP
186
SCLTT
191
AVPSP
196
SKPRT
201
AQLVL
206
QRMQQ
211
FKRAD
216
PERLR
221
HASEE
226
CSLEA
231
AREEN
236
VPKDP
241
QEEMM
246
AGNVY
251
GLGPP
256
APESD
261
AAVAL
266
TLQQE
271
FARVG
276
ASAHD
281
DSLEE
286
KGLFF
291
CQICQ
296
KNLSA
301
MNVTR
306
REQHV
311
NRCLD
316
EAEKT
321
LRPSV
326
PQIPE
331
CPICG
336
KPFLT
341
LKSRT
346
SHLKQ
351
CAVKM
356
EVGPQ
361
LLLQA
366
VRLQT
371
AQPEG
376
SSSPP
381
MFSFS
386
DHSRG
391
LKRRG
396
PTSKK
401
EPRKR
406
RKVDE
411
APSED
416
LLVAM
421
ALSRS
426
EMEPG
431
AAVPA
436
LRLES
441
AFSER
446
IRPEA
451
ENKSR
456
KKKPP
461
VSPPL
466
LLVQD
471
SETTG
476
RQIED
481
RVALL
486
LSEEV
491
ELSST
496
PPLPA
501
SRILK
506
EGWER
511
AGQCP
516
PPPER
521
KQSFL
526
WEGSA
531
LTGAW
536
AMEDF
541
YTARL
546
VPPLV
551
PQRPA
556
QGLMQ
561
EPVPP
566
LVPPE
571
HSELS
576
ERRSP
581
ALHGT
586
PTAGC
591
GSRGP
596
SPSAS
601
QREHQ
606
ALQDL
611
VDLAR
616
EGLSA
621
SPWPG
626
SGGLA
631
GSEGT
636
AGLDV
641
VPGGL
646
PLTGF
651
VVPSQ
656
DKHPD
661
RGGRT
666
LLSLG
671
LLVAD
676
FGAMV
681
NNPHL
686
SDVQF
691
QTDSG
696
EVLYA
701
HKFVL
706
YARCP
711
LLIQY
716
VNNEG
721
FSAVE
726
DGVLT
731
QRVLL
736
GDVST
741
EAART
746
FLHYL
751
YTADT
756
GLPPG
761
LSSEL
766
SSLAH
771
RFGVS
776
ELVHL
781
CEQVP
786
IATDS
791
EGKPW
796
EEKEA
801
ENCES
806
RAENF
811
QELLR
816
SMWAD
821
EEEEA
826
ETLLK
831
SKDHE
836
EDQEN
841
VNEAE
846
MEEIY
851
EFAAT
856
QRKLL
861
QEERA
866
AGAGE
871
DADWL
876
EGGSP
881
VSGQL
886
LAGVQ
891
VQKQW
896
DKVEE
901
MEPLE
906
PGRDE
911
AATTW
916
EKMGQ
921
CALPP
926
PQGQH
931
SGARG
936
AEAPE
941
QEAPE
946
EALGH
951
SSCSS
956
PSRDC
961
QAERK
966
EGSLP
971
HSDDA
976
GDYEQ
981
LFSST
986
QGEIS
991
EPSQI
996
TSEPE
1001
EQSGA
1006
VRERG
1011
LEVSH
1016
RLAPW
1021
QASPP
1026
HPCRF
1031
LLGPP
1036
QGGSP
1041
RGSHH
1046
TSGSS
1051
LSTPR
1056
SRGGT
1061
SQVGS
1066
PTLLS
1071
PAVPS
1076
KQKRD
1081
RSILT
1086
LSKEP
1091
GHQKG
1096
KERRS
1101
VLECR
1106
NKGVL
1111
MFPEK
1116
SPSID
1121
LTQSN
1126
PDHSS
1131
SRSQK
1136
SSSKL
1141
NEEDE
1146
VILLL
1151
DSDEE
1156
LELEQ
1161
TKMKS
1166
ISSDP
1171
LEEKK
1176
ALEIS
1181
PRSCE
1186
LFSII
1191
DVDAD
1196
QEPSQ
1201
SPPRS
1206
EAVLQ
1211
QEDEG
1216
ALPEN
1221
RGSLG
1226
RRGAP
1231
WLFCD
1236
RESSP
1241
SEAST
1246
TDTSW
1251
LVPAT
1256
PLASR
1261
SRDCS
1266
SQTQI
1271
SSLRS
1276
GLAVQ
1281
AVTQH
1286
TPRAS
1291
VGNRE
1296
GNEVA
1301
QKFSV
1306
IRPQT
1311
PPPQT
1316
PSSCL
1321
TPVSP
1326
GTSDG
1331
RRQGH
1336
RSPSR
1341
PHPGG
1346
HPHSS
1351
PLAPH
1356
PISGD
1361
RAHFS
1366
RRFLK
1371
HSPPG
1376
PSFLN
1381
QTPAG
1386
EVVEV
1391
GDSDD
1396
EQEVA
1401
SHQAN
1406
RSPPL
1411
DSDPP
1416
IPIDD
1421
CCWHM
1426
EPLSP
1431
IPIDH
1436
WNLER
1441
TGPLS
1446
TSSPS
1451
RRMNE
1456
AADSR
1461
DCRSP
1466
GLLDT
1471
TPIRG
1476
SCTTQ
1481
RKLQE
1486
KSSGA
1491
GSLGN
1496
SRPSF
1501
LNSAL
1506
WDVWD
1511
GEEQR
1516
PPETP
1521
PPAQM
1526
PSAGG
1531
AQKPE
1536
GLETP
1541
KGANR
1546
KKNLP
1551
PKVPI
1556
TPMPQ
1561
YSIME
1566
TPVLK
1571
KELDR
1576
FGVRP
1581
LPKRQ
1586
MVLKL
1591
KEIFQ
1596
YTHQT
1601
LDSDS
1606
EDESQ
1611
SSQPL
1616
LQAPH
1621
CQTLA
1626
SQTYK
1631
PSRAG
1636
VHAQQ
1641
EATTG
1646
PGAHR
1651
PKGPA
1656
KTKGP
1661
RHQRK
1666
HHESI
1671
TPPSR
1676
SPTKE
1681
APPGL
1686
NDDAQ
1691
IPASQ
1696
ESVAT
1701
SVDGS
1706
DSSLS
1711
SQSSS
1716
SCEFG
1721
AAFES
1726
AGEEE
1731
GEGEV
1736
SASQA
1741
AVQAA
1746
DTDEA
1751
LRCYI
1756
RSKPA
1761
LYQKV
1766
LLYQP
1771
FELRE
1776
LQAEL
1781
RQNGL
1786
RVSSR
1791
RLLDF
1796
LDTHC
1801
ITFTT
1806
AATRR
1811
EKLQG
1816
RRRQP
1821
RGKKK
1826
VERN
1831
Mutation Information
DNA mutation:
c.C752T
Peptide Range:
239 ~ 263
Mut AA position:
251 (13 in Wild Type peptide)
Alignment
Wild Type:
"ENVPKDPQEEMMAGNVYGLGPPAPE
||||||||||||.||||||||||||
Mutant:
ENVPKDPQEEMMVGNVYGLGPPAPE"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) SLX4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
ENVPKDPQEEMMVGNVYGLGPPAPE
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT