Immunogenicity 4601

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LONRF2
Transcript ID
NM_198461
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (754 aa)
MSPEP
1
VPPPP
6
PPQCP
11
GCDRA
16
EPIAQ
21
RLEEG
26
DEAFR
31
AGDYE
36
MAAEL
41
FRSML
46
AGLAQ
51
PDRGL
56
CLRLG
61
DALAR
66
AGRLP
71
EALGA
76
FRGAA
81
RLGAL
86
RPEEL
91
EELAG
96
GLVRA
101
VGLRD
106
RPLSA
111
ENPGG
116
EPEAP
121
GEGGP
126
APEPR
131
APRDL
136
LGCPR
141
CRRLL
146
HKPVT
151
LPCGL
156
TVCKR
161
CVEPG
166
PARPQ
171
VRRVN
176
VVLSG
181
LLEKC
186
FPAEC
191
RLRRL
196
AGQAR
201
SLQRQ
206
QQPEA
211
ALLRC
216
DQALE
221
LAPDD
226
NSLLL
231
LRAEL
236
YLTMK
241
NYEQA
246
LQDAS
251
AACQN
256
EPLLI
261
KGHQV
266
KAQAL
271
SGLGR
276
SKEVL
281
KEFLY
286
CLALN
291
PECNS
296
VKKEA
301
QKVMC
306
EVLFS
311
ATANV
316
HENLT
321
SSIQS
326
RLKAQ
331
GHSHM
336
NAQAL
341
LEEGD
346
AGSSE
351
NSSEK
356
SDMLG
361
NTNSS
366
VLYFI
371
LGLHF
376
EEDKK
381
ALESI
386
LPTAP
391
SAGLK
396
RQFPD
401
DVEDA
406
PDLNA
411
PGKIP
416
KKDLS
421
LQRSP
426
NSETE
431
ESQGL
436
SLDVT
441
DFECA
446
LCMRL
451
LFEPV
456
TTPCG
461
HTFCL
466
KCLER
471
CLDHA
476
PHCPL
481
CKDKL
486
SELLA
491
SRNFN
496
ITVLA
501
EELIF
506
RYLPD
511
ELSDR
516
KRIYD
521
EEMSE
526
LSNLT
531
RDVPI
536
FVCAM
541
AFPTV
546
PCPLH
551
VFEPR
556
YRLMI
561
RRCME
566
TGTKR
571
FGMCL
576
SAEHA
581
GLSEY
586
GCMLE
591
IKDVR
596
TFPDG
601
SSVVD
606
AIGIS
611
RFRVL
616
SHRHR
621
DGYNT
626
ADIEY
631
LEDEK
636
VEGPE
641
YEELA
646
ALHDS
651
VHQQS
656
VSWFA
661
SLQDR
666
MKEQI
671
LSHFG
676
VMPDR
681
EPEPQ
686
SNPSG
691
PAWSW
696
WILAV
701
LPLER
706
KAQLA
711
ILGMT
716
SLKER
721
LLAIR
726
RILVI
731
ITRKM
736
NSRQE
741
LANAR
746
ERNN
751
Mutation Information
DNA mutation:
None
Peptide Range:
403 ~ 427
Mut AA position:
415 (13 in Wild Type peptide)
Alignment
Wild Type:
"FPDDVEDAPDLNAPGKIPKKDLSLQ
||||||||||||.||||||||||||
Mutant:
FPDDVEDAPDLNTPGKIPKKDLSLQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LONRF2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay