Immunogenicity 4614
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
LRIT1
Transcript ID
NM_015613
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO
No TCR info found!
Full length protein sequence (623 aa)
MRVAL
1
GMLWL
6
LALAW
11
PPQAR
16
GFCPS
21
QCSCS
26
LHIMG
31
DGSKA
36
RTVVC
41
NDPDM
46
TLPPA
51
SIPPD
56
TSRLR
61
LERTA
66
IRRVP
71
GEAFR
76
PLGRL
81
EQLWL
86
PYNAL
91
SELNA
96
LMLRG
101
LRRLR
106
ELRLP
111
GNRLA
116
AFPWA
121
ALRDA
126
PKLRL
131
LDLQA
136
NRLSA
141
VPAEA
146
ARFLE
151
NLTFL
156
DLSSN
161
QLMRL
166
PQELI
171
VSWAH
176
LETGI
181
FPPGH
186
HPRRV
191
LGLQD
196
NPWAC
201
DCRLY
206
DLVHL
211
LDGWA
216
PNLAF
221
IETEL
226
RCASP
231
RSLAG
236
VAFSQ
241
LELRK
246
CQGPE
251
LHPGV
256
ASIRS
261
LLGGT
266
ALLRC
271
GATGV
276
PGPEM
281
SWRRA
286
NGRPL
291
NGTVH
296
QEVSS
301
DGTSW
306
TLLGL
311
PAVSH
316
LDSGD
321
YICQA
326
KNFLG
331
ASETV
336
ISLIV
341
TEPPT
346
STEHS
351
GSPGA
356
LWART
361
GGGGE
366
AAAYN
371
NKLVA
376
RHVPQ
381
IPKPA
386
VLATG
391
PSVPS
396
TKEEL
401
TLEHF
406
QMDAL
411
GELSD
416
GRAGP
421
SEARM
426
VRSVK
431
VVGDT
436
YHSVS
441
LVWKA
446
PQAKN
451
TTAFS
456
VLYAV
461
FGQHS
466
MRRVI
471
VQPGK
476
TRVTI
481
TGLLP
486
KTKYV
491
ACVCV
496
QGLVP
501
RKEQC
506
VIFST
511
NEVVD
516
AENTQ
521
QLINV
526
VVISV
531
AIVIA
536
LPLTL
541
LVCCS
546
ALQKR
551
CRKCF
556
NKDST
561
EATVT
566
YVNLE
571
RLGYS
576
EDGLE
581
ELSRH
586
SVSEA
591
DRLLS
596
ARSSV
601
DFQAF
606
GVKGG
611
RRINE
616
YFC
621
Mutation Information
DNA mutation:
None
Peptide Range:
365 ~ 389
Mut AA position:
377 (13 in Wild Type peptide)
Alignment
Wild Type:
"TGGGGEAAAYNNKLVARHVPQIPKP
||||||||||||.||||||||||||
Mutant:
TGGGGEAAAYNNTLVARHVPQIPKP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) LRIT1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay