Immunogenicity 465
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RPTOR
Transcript ID
None
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (1335 aa)
MESEM
1
LQSPL
6
LGLGE
11
EDEAD
16
LTDWN
21
LPLAF
26
MKKRH
31
CEKIE
36
GSKSL
41
AQSWR
46
MKDRM
51
KTVSV
56
ALVLC
61
LNVGV
66
DPPDV
71
VKTTP
76
CARLE
81
CWIDP
86
LSMGP
91
QKALE
96
TIGAN
101
LQKQY
106
ENWQP
111
RARYK
116
QSLDP
121
TVDEV
126
KKLCT
131
SLRRN
136
AKEER
141
VLFHY
146
NGHGV
151
PRPTV
156
NGEVW
161
VFNKN
166
YTQYI
171
PLSIY
176
DLQTW
181
MGSPS
186
IFVYD
191
CSNAG
196
LIVKS
201
FKQFA
206
LQREQ
211
ELEVA
216
AINPN
221
HPLAQ
226
MPLPP
231
SMKNC
236
IQLAA
241
CEATE
246
LLPMI
251
PDLPA
256
DLFTS
261
CLTTP
266
IKIAL
271
RWFCM
276
QKCVS
281
LVPGV
286
TLDLI
291
EKIPG
296
RLNDR
301
RTPLG
306
ELNWI
311
FTAIT
316
DTIAW
321
NVLPR
326
DLFQK
331
LFRQD
336
LLVAS
341
LFRNF
346
LLAER
351
IMRSY
356
NCTPV
361
SSPRL
366
PPTYM
371
HAMWQ
376
AWDLA
381
VDICL
386
SQLPT
391
IIEEG
396
TAFRH
401
SPFFA
406
EQLTA
411
FQVWL
416
TMGVE
421
NRNPP
426
EQLPI
431
VLQVL
436
LSQVH
441
RLRAL
446
DLLGR
451
FLDLG
456
PWAVS
461
LALSV
466
GIFPY
471
VLKLL
476
QSSAR
481
ELRPL
486
LVFIW
491
AKILA
496
VDSSC
501
QADLV
506
KDNGH
511
KYFLS
516
VLADP
521
YMPAE
526
HRTMT
531
AFILA
536
VIVNS
541
YHTGQ
546
EACLQ
551
GNLIA
556
ICLEQ
561
LNDPH
566
PLLRQ
571
WVAIC
576
LGRIW
581
QNFDS
586
ARWCG
591
VRDSA
596
HEKLY
601
SLLSD
606
PIPEV
611
RCAAV
616
FALGT
621
FVGNS
626
AERTD
631
HSTTI
636
DHNVA
641
MMLAQ
646
LVSDG
651
SPMVR
656
KELVV
661
ALSHL
666
VVQYE
671
SNFCT
676
VALQF
681
IEEEK
686
NYALP
691
SPATT
696
EGGSL
701
TPVRD
706
SPCTP
711
RLRSV
716
SSYGN
721
IRAVA
726
TARSL
731
NKSLQ
736
NLSLT
741
EESGG
746
AVAFS
751
PGNLS
756
TSSSA
761
SSTLG
766
SPENE
771
EHILS
776
FETID
781
KMRRA
786
SSYSS
791
LNSLI
796
GVSFN
801
SVYTQ
806
IWRVL
811
LHLAA
816
DPYPE
821
VSDVA
826
MKVLN
831
SIAYK
836
ATVNA
841
RPQRV
846
LDTSS
851
LTQSA
856
PASPT
861
NKGVH
866
IHQAG
871
GSPPA
876
SSTSS
881
SSLTN
886
DVAKQ
891
PVSRD
896
LPSGR
901
PGTTG
906
PAGAQ
911
YTPHS
916
HQFPR
921
TRKMF
926
DKGPE
931
QTADD
936
ADDAA
941
GHKSF
946
ISATV
951
QTGFC
956
DWSAR
961
YFAQP
966
VMKIP
971
EEHDL
976
ESQIR
981
KEREW
986
RFLRN
991
SRVRR
996
QAQQV
1001
IQKGI
1006
TRLDD
1011
QIFLN
1016
RNPGV
1021
PSVVK
1026
FHPFT
1031
PCIAV
1036
ADKDS
1041
ICFWD
1046
WEKGE
1051
KLDYF
1056
HNGNP
1061
RYTRV
1066
TAMEY
1071
LNGQD
1076
CSLLL
1081
TATDD
1086
GAIRV
1091
WKNFA
1096
DLEKN
1101
PEMVT
1106
AWQGL
1111
SDMLP
1116
TTRGA
1121
GMVVD
1126
WEQET
1131
GLLMS
1136
SGDVR
1141
IVRIW
1146
DTDRE
1151
MKVQD
1156
IPTGA
1161
DSCVT
1166
SLSCD
1171
SHRSL
1176
IVAGL
1181
GDGSI
1186
RVYDR
1191
RMALS
1196
ECRVM
1201
TYREH
1206
TAWVV
1211
KASLQ
1216
KRPDG
1221
HIVSV
1226
SVNGD
1231
VRIFD
1236
PRMPE
1241
SVNVL
1246
QIVKG
1251
LTALD
1256
IHPQA
1261
DLIAC
1266
GSVNQ
1271
FTAIY
1276
NSSGE
1281
LINNI
1286
KYYDG
1291
FMGQR
1296
VGAIS
1301
CLAFH
1306
PHWPH
1311
LAVGS
1316
NDYYI
1321
SVYSV
1326
EKRVR
1331
Mutation Information
DNA mutation:
None
Peptide Range:
746 ~ 768
Mut AA position:
755 (10 in Wild Type peptide)
Alignment
Wild Type:
"---EESGGAVAFS----------
|||||||||.
Mutant:
SLTEESGGAVAFFPGNLSTSSSA"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) RPTOR
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay