Immunogenicity 4690

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
IQCF1
Transcript ID
NM_152397
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (205 aa)
MEEKQ
1
PQKTK
6
EPSKE
11
DEPQQ
16
KEMPT
21
HLSLG
26
AESKA
31
EAKTP
36
VLVET
41
QTVDN
46
ANEKS
51
EKPPE
56
NQKKL
61
SDKDT
66
VATKI
71
QAWWR
76
GTLVR
81
RALLH
86
AALSA
91
CIIQC
96
WWRLI
101
LSKIL
106
KKRRQ
111
AALEA
116
FSRKE
121
WAAVT
126
LQSQA
131
RMWRI
136
RRRYC
141
QVLNA
146
VRIIQ
151
AYWRC
156
RSCAS
161
RGFIK
166
GQYRV
171
TANQL
176
HLQLE
181
ILLDS
186
GPCIV
191
TECIP
196
FSIKE
201
Mutation Information
DNA mutation:
None
Peptide Range:
68 ~ 92
Mut AA position:
80 (13 in Wild Type peptide)
Alignment
Wild Type:
"KDTVATKIQAWWRGTLVRRALLHAA
||||||||||||.||||||||||||
Mutant:
KDTVATKIQAWWWGTLVRRALLHAA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) IQCF1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay